Sökning: "Pax6"
Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet Pax6.
1. Genetic analysis of genes found on the 4th chromosome of Drosophila - emphasizing the developmental context of Pax6
Sammanfattning : The small size and the lack of recombination set the fourth chromosome of Drosophila melanogaster apart from the other chromosomes. I have shown that the Minute gene on chromosome 4, earlier named Minute-4, encodes the ribosomal protein RpS3A. Two Pax6 genes, eyeless (ey) and twin of eyeless (toy) are also located on chromosome 4. LÄS MER
2. Human neural stem cells: region-specific properties and prospects for cell therapy
Sammanfattning : Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. LÄS MER
3. Aniridia-related keratopathy : structural changes, signaling pathways and clinical aspects
Sammanfattning : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. LÄS MER
4. Mechanisms controlling striatal projection neurone generation, from patterning to early differentiation
Sammanfattning : The striatum is part of the telencephalon, the most anterior part of the vertebrate brain. From when it first can be identified, telencephalic morphology is highly complex and a wide range of mechanisms has been suggested to participate in its induction, patterning and neurogenesis. LÄS MER
5. On Aniridia in Sweden and Norway
Sammanfattning : Introduction Aniridia (iris more or less missing), is a congenital, dominant, inherited, serious and sight-threatening disease, most often appearing as an isolated eye disorder. It is caused by mutations in the PAX6 gene, the master gene of the development of the eye. Typically, Aniridia causes severe visual impairment. LÄS MER