Sökning: "Patrik Sundström"

Hittade 5 avhandlingar innehållade orden Patrik Sundström.

  1. 1. B cell migration to healthy and malignant gastrointestinal mucosa

    Författare :Patrik Sundström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 2. Single-chain antibody construction and functional mapping of the monoclonal antibody TS1 : Its interaction with the antigen and the anti-idiotype

    Författare :Patrik Holm; Birgitta Sundström; Per-Åke Nygren; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemistry; Kemi; Chemistry; Kemi; Biomedicin; Biomedical Laboratory Science;

    Sammanfattning : The aims of this study are to synthesize and produce a single-chain antibody (scFv) of the anti-cytokeratin 8 monoclonal IgG antibody TS1 and to functionally map amino acid residues important for the interaction with its antigen and the anti-idiotypic antibody TS1. The TS1 antibody has been shown to be effective in binding cytokeratin 8 (CK8) expressed in tumors in vivo and is proposed to be useful in immunotargeting and/or immunotherapy. LÄS MER

  4. 3. Functional mapping and in vivo metabolism of the monoclonal antibody TS1 and its single-chain fragment : Its interaction with the antigen and the anti-idiotype

    Författare :Patrik Holm; Birgitta Sundström; Lars Gedda; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single-chain antibody; functional mapping; site-directed mutagenesis; immune complex; metabolism; Molecular biology; Molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Sammanfattning : Antibodies are proteins capable of specific interactions to a wide range of molecules. These interactions are facilitated by the complementary determining regions (CDR).Carcinomas are the most common of human cancers and they release significant amount of cytokeratins (CK) in the necrotic areas of the tumors. LÄS MER

  5. 4. Villkorat förtroende : Normer och rollförväntningar i relationen mellan politiker och tjänstemän i Regeringskansliet

    Författare :Cajsa Niemann; Göran Sundström; Rune Premfors; Patrik Hall; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; political institutions; political elites; politicians; civil servants; core executives; government; government offices; state organisation; institutional change and stability; norms; roles; role expectations; trust; organisational theory; Sweden; Political Science; statsvetenskap;

    Sammanfattning : The relationship between politicians and civil servants is ambiguous and potentially problematic in democratic terms. The aim of the thesis is to examine this relationship in the Swedish core executive, Regeringskansliet. More specifically, the analysis emphasises the respective role expectations of the two groups when interacting with each other. LÄS MER

  7. 5. Styrning bakom kulisserna : Regeringskansliets politiska staber och regeringens styrningskapacitet

    Författare :Anna Ullström; Rune Premfors; Göran Sundström; Patrik Hall; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; core executives; government; government offices; ministerial staff; political advisers; political appointees; political elites; steering; governance; policy capacity; political institutions; state organization; political ethnography; regeringskansliet; regeringen; politiska staber; politiskt sakkunniga; politiskt anställda; politiska eliter; styrning; styrningskapacitet; politiska institutioner; statens organisering; politisk etnografi; Political science; Statsvetenskap; Ethnography; Etnografi; Public sector research; Forskning om offentlig sektor; Political Science; statsvetenskap;

    Sammanfattning : This thesis analyses one of the less explored areas of Swedish politics: the political appointees in the ministerial staffs of the Swedish core executive. The study draws attention to the everyday life of the ministerial staff in order to give an idea of their function: What do the political appointees do? How is the work of the ministerial staffs organized? How is policy coordinated at the political level? The main empirical focus of this thesis is the 2002-2006 term of office. LÄS MER