Sökning: "Patrik Ek"

Hittade 2 avhandlingar innehållade orden Patrik Ek.

  1. 1. Mass Spectrometry with Electrospray Ionization from an Adjustable Gap

    Författare :Patrik Ek; Åsa Emmer; Johan Roeraade; Per M. Claesson; Ulrika Nilsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Electrospray ionization; mass spectrometry; nanoelectrospray; ESI; MS; chip; emitter; gap; liquid bridge; nozzle; peptides; Analytical chemistry; Analytisk kemi;

    Sammanfattning : In this thesis the fabrication and analytical evaluation of two new electrospray emitters utilized for mass spectrometry analysis is presented. The emitters are based on a new concept, where the spray orifice can be varied in size. The thesis is based on two papers. All present-day nanoelectrospray emitters have fixed dimensions. LÄS MER

  3. 2. New methods for sensitive analysis with nanoelectrospray ionization mass spectrometry

    Författare :Patrik Ek; Johan Roeraade; Åsa Emmer; Andries P. Bruins; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; electrospray ionization; nanoelectrospray ionization; adjustable gap; emitter; miniaturization; improved sensitivity; nanoliter picoliter sample volumes; Alzheimer’s disease; amyloid-beta Aβ ; Analytical chemistry; Analytisk kemi;

    Sammanfattning : In this thesis, new methods that address some current limitations in nanoelectrospray mass spectrometry (nESI-MS) analysis are presented. One of the major objectives is the potential gain in sensitivity that can be obtained when employing the proposed techniques. LÄS MER