Sökning: "Pathology"

Visar resultat 16 - 20 av 925 avhandlingar innehållade ordet Pathology.

1. 16. SOD1 prions transmit templated aggregation and fatal ALS-like disease

   Författare :Elaheh Ekhtiari Bidhendi; Thomas Brännström; Stefan L. Marklund; Peter M. Andersen; Inger Nennesmo; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; amyotrophic lateral sclerosis; SOD1; prion; neurodegeneration; strain; seeding; protein misfolding; protein aggregation; propagation; transgenic mice; Pathology; patologi; Neurology; neurologi;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disease characterized by a progressive degeneration of the upper and lower motor neurons. The resulting paresis begins focally, usually in one muscle, and spreads contiguously, leading to muscle wasting, progressive paralysis and eventually death. LÄS MER

3. 17. Mutant superoxide dismutase-1-caused pathogenesis in amyotrophic lateral sclerosis

   Författare :Daniel Bergemalm; Stefan Marklund; Thomas Brännström; Peter Andersen; Caterina Bendotti; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; mitochondria; proteome; transgenic mice; inclusion; Clinical chemistry; Klinisk kemi; biokemi; Biochemistry; neurologi; Neurology; Clinical Chemistry; klinisk kemi; patologi; Pathology;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a devastating disease that affects people in their late mid-life, with fatal outcome usually within a few years. The progressive degeneration of neurons responsible for muscle movement (motor neurons) throughout the central nervous system (CNS) leads to muscle wasting and paralysis, and eventually affects respiratory function. LÄS MER

4. 18. Immunopathogenesis of relapsing fever borreliosis

   Författare :Marie Andersson; Sven Bergström; Betty P. Guo; Janis J. Weis; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Relapsing fever; Borrelia; mouse models; biological barriers; pathology; chemokines; cytokines; pregnancy; Molecular biology; Molekylärbiologi;

   Sammanfattning : Relapsing fever (RF) is caused by different species of Borrelia transmitted by soft ticks or by the human body louse. Illness is characterized by reappearing peaks of high concentrations of spirochetes in blood, concordant with fever peaks separated by asymptomatic periods. LÄS MER

5. 19. Aspects on in vivo imaging techniques for diagnostics of pigmented skin lesions

   Författare :Karin Terstappen; Göteborgs universitet; []
   Nyckelord :Melanoma; pigmented nevi; basal cell carcinoma; differential diagnosis; dermoscopy; spectrophotometric intracutaneous analysis; pathology;

   Sammanfattning : Abstract Problem: Non-invasive diagnostic techniques to facilitate diagnosis of pigmented skin lesions (PSL) are being developed. Dermoscopy and SIAscopy are two such techniques, and they are evaluated in this thesis. LÄS MER

7. 20. Free radicals in cellular pathology : effects of ionizing radiation on cultured macrophages, submandibular salivary glands and mesenteric mast cells

   Författare :Kisia Abok; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER