Sökning: "Parkinsonism"

Visar resultat 6 - 10 av 46 avhandlingar innehållade ordet Parkinsonism.

  1. 6. Proteomic Characterization of Induced Developmental Neurotoxicity

    Författare :Henrik Alm; Lennart Dencker; R Stuart Cobb; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Brain Development; Neurotoxicity; 2D-DIGE; Brain Growth Spurt; Polybrominated Diphenyl Ether; Neonatal; Striatum; Hippocampus; Cerebral Cortex; Parkinsonism; Dyskinesia; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : The developing brain goes through a number of developmental periods during which it displays an increased sensitivity to exogenous disturbances. On such period is the so called “Brain growth spurt” (BGS) which in humans takes place starting from the third trimester of pregnancy and throughout the first few years of life. LÄS MER

  2. 7. Recessive parkinsonism, mitochondria and translational regulation

    Författare :Jeff Blackinton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Three genes are known to cause recessive forms of Parkinson disease (PD) in humans: parkin, PINK1 and DJ-1. Of these, the rarest is DJ-1; less than fifty known cases worldwide are due to mutations in DJ-1. LÄS MER

  3. 8. Functional MRI characterization of animal models of parkinsonism

    Författare :Cyril Monnot; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Parkinson's disease (PD) is the second most common neurological disorder. It is characterized by the progressive development of motor symptoms - bradykinesia, resting tremor, muscular rigidity and difficulty with postural control - which serve as criterias for its clinical diagnosis. LÄS MER

  4. 9. Imaging Studies of Olfaction in Health and Parkinsonism

    Författare :Charalampos Georgiopoulos; Elna-Marie Larsson; Maria Engström; Nil Dizdar; Helene Zachrisson; Asta Kristine Håberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Olfactory loss is a common non-motor symptom of Parkinson’s disease (PD), often preceding the cardinal motor symptoms of the disease. The aim of this thesis was to: (a) evaluate whether olfactory examination can increase diagnostic accuracy, and (b) study the structural and functional neural basis of olfactory dysfunction in PD with different applications of Magnetic Resonance Imaging (MRI). LÄS MER

  5. 10. MPTP-induced behavioural deficits in mice : validity and utility of a model of Parkinsonism

    Författare :Anders Fredriksson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER