Sökning: "Paraganglioma"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet Paraganglioma.

  1. 1. Nuclear medicine imaging and treatment in pheochromocytoma, paraganglioma, and role of the new tracer 11C-hydroxy ephedrine in diabetes mellitus

    Författare :Achyut Ram Vyakaranam; Anders Sundin; Elin Trägårdh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11C-HED; PRRT; TCTTV; Non-Invasive imaging; symapthetic innervation; pheochromocytoma; paraganglioma; NETs; RECIST 1.1; Oncology; Onkologi; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : Carbon-11 hydroxy ephedrine (11C-HED) is a norepinephrine analog which binds to the norepinephrine receptor present in adrenal medulla, lung, liver and pancreas. 11C-HED-positron emission tomography with concomitant computed tomography (PET/CT) can image these organs. LÄS MER

  2. 2. Genetic Alterations in Pheochromocytoma and Paraganglioma

    Författare :Jenny Welander; Peter Söderkvist; Oliver Gimm; Mercedes Robledo; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pheochromocytoma; paraganglioma; genetics; sequencing; cancer; mutation;

    Sammanfattning : Pheochromocytomas and paragangliomas are neuroendocrine tumors that arise from neural crest-derived cells of the adrenal medulla and the extra-adrenal paraganglia. They cause hypertension due to an abnormally high production of catecholamines (mainly adrenaline and noradrenaline), with symptoms including recurrent episodes of headache, palpitations and sweating, and an increased risk of cardiovascular disease. LÄS MER

  3. 3. Incidentally discovered adrenal tumours, adrenal metastases and pheochromocytomas - Clinical and epidemiological aspects

    Författare :Andreas Muth; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Incidental Findings; Adrenal incidentaloma; Adrenal Gland Neoplasms; Adrenalectomy; Follow-Up Studies; Quality of Life; Pheochromocytoma epidemiology; Pheochromocytoma genetics; Paraganglioma epidemiology; Paraganglioma genetics;

    Sammanfattning : With increasing use of high resolution radiological imaging incidentally discovered adrenal tumours (adrenal incidentalomas, AI) have become a common clinical problem. The aim of work-up and follow-up of patients with AI is to detect malignant (primary or metastatic) and/or hormone-producing tumours. LÄS MER

  4. 4. Pheochromocytoma and abdominal paraganglioma : clinical and genetic aspects

    Författare :Elisabet Edström Elder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pheochromocytomas; abdominal paragangliomas; RET; MEN 2A; tumour development; chromosome 1; comparative genomic hybridisation; in situ hybridization; loss of heterozygosity.;

    Sammanfattning : Pheochromocytomas and abdominal paragangliomas are rare catecholamine producing tumours arising from sympathoadrenal paraganglia located within and outside of the adrenal medulla, respectively. The great majority of tumours are benign and cured by surgery. LÄS MER

  5. 5. Genetic and molecular background of pheochromocytoma and paraganglioma

    Författare :Adam Stenman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pheochromocytomas (PCC) and abdominal paragangliomas (PGL), collectively denoted PPGL, are neuroendocrine tumors (NET) with a highly diverse genetic and molecular etiology, arisen in the adrenal medulla and abdominal paraganglia respectively. The tumors often cause cardiovascular symptoms due to the high production of catecholamines, and malignancy occurs in 10% of the PCCs and 30% of the PGLs. LÄS MER