Sökning: "PapG adhesin"
Visar resultat 6 - 9 av 9 avhandlingar innehållade orden PapG adhesin.
6. Febrile Urinary Tract Infection: P fimbriae, Innate Host Response and Bacteremia
Sammanfattning : Urinary tract infections (UTI) are among the most common human infections, and febrile UTI with bacteremia the most severe form. The relation between bacteria and host decides disease severity. The dominating uropathogen is Escherichia coli (E. coli). LÄS MER
7. Novel tools for the study and diagnosis of bacterial infections : exploring the intersection of microbiology and microfabrication
Sammanfattning : The alarming increase in antibiotic resistance calls for new approaches to study and diagnose bacterial infections. In my thesis, I worked at the intersection of microbiology, microfabrication, and optical probes to develop novel diagnostic and screening assays for microbiology and elucidate bacterial pathogenesis in urinary tract infections (UTI). LÄS MER
8. Molecular determinants of disease severity in urinary tract infection
Sammanfattning : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. LÄS MER
9. Combinatorial Synthesis of Pilicides
Sammanfattning : This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i. LÄS MER