Sökning: "PapG adhesin"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden PapG adhesin.

  1. 1. Potent inhibitors of uropathogenic E. coli papG adhesins; Synthesis, conformational studies and biological evaluation of galabiose derivatives and synthesis of glycosphingolipid analogues

    Detta är en avhandling från Organic Chemistry, Lund University

    Författare :Jörgen Ohlsson; Lunds universitet.; Lund University.; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Glycosphingolipid analogue; PapG adhesin; Esherichia coli; Galabiose analogues; Inhibitors; Glycoconjugates;

    Sammanfattning : The importance of carbohydrates in biological systems has become evident during the last fifty years. It is well known that pathogenic bacteria and viruses attach to glycoconjugates present at mammalian cell surfaces, and that this attachment is a prerequisite for the later stages of infection. LÄS MER

  2. 2. The importance of Escherichia coli fimbriae in urinary tract infection

    Detta är en avhandling från Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Författare :Mats Söderhäll; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Urinary tract infection (UTI) is a major bacterial infectious disease among women. Uropathogenic Escherichia coli is the most dominant causative agent. LÄS MER

  3. 3. Synthesis, conformational analysis, and biological evaluation of peptides from E. coli P pilus proteins

    Detta är en avhandling från Organic Chemistry, Lund University

    Författare :Katarina Flemmer Karlsson; Lunds universitet.; Lund University.; [1997]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; CD spectroscopy; peptide structure; ELISA; solid-phase peptide synthesis; peptide; P pili; chaperone; Organic chemistry; Organisk kemi;

    Sammanfattning : Many bacteria utilize hairlike protein appendages (pili) to attach themselves to mucosal cell surfaces in the host organism. The pilus is assembled from protein subunits synthesized inside the bacteria and transported to the outer cell wall for incorporation into the growing pilus. LÄS MER

  4. 4. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

    Detta är en avhandling från Division of Microbiology, Immunology and Glycobiology - MIG

    Författare :Göran Bergsten; Lunds universitet.; Lund University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; IL-8; IL-6; neutrophils; GFP; mucosal host response; Type 1 fimbriae; P fimbriae; adherence; virulence factors; regulation; deliberate colonisation; Escherichia coli 83972; Urinary tract infection; asymptomatic bacteriuria;

    Sammanfattning : Popular Abstract in Swedish Urinvägsinfektioner (UVI) är en av våra vanligaste infektionssjukdomar och orsakas oftast av bakterien Escherichia coli (E. coli). Infektionernas svårighetsgrad varierar, beroende på samspelet mellan bakterie och värd. LÄS MER

  5. 5. Antiadhesive agents targeting uropathogenic Escherichia coli Multivariate studies of protein-protein and protein-carbohydrate interactions

    Detta är en avhandling från Umeå : Kemi

    Författare :Andreas Larsson; Umeå universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Antibacterial; pili; antiadhesive agents; structure based design; statistical molecular design; 2-pyridone; amino acid derivative; galabiose; enaminone; SPR; ELISA; QSAR; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes studies directed towards development of novel antiadhesive agents, with particular emphasis on compounds that prevent attachment of bacteria to a host-cell. Three different proteins involved in the assembly or function of adhesive pili in uropathogenic Escherichia coli have been targeted either by rational structure based design or statistical molecular methods. LÄS MER