Sökning: "Pancreatic cancer"

Visar resultat 16 - 20 av 155 avhandlingar innehållade orden Pancreatic cancer.

  1. 16. Psychological responses to gastrointestinal cancer

    Författare :Karin Nordin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Gastrointestinal cancer; coping; anxiety; depression; subjectivedistress; prediction; psychometric analysis; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : The overall aim of the present thesis is to gain knowledge about psychological distress and adjustment in gastrointestinal cancer patients (colon, rectum, gastric, pancreatic or biliary) at various phases of their disease.Reactions to the diagnosis, anxiety, depression and coping were investigated in newly diagnosed patients (n=139). LÄS MER

  3. 17. Biomarkers in pancreatic and other periampullary cancers - some familiar and one new

    Författare :Margareta Heby; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periampullary adenocarcinoma; Pancreatic cancer; Biomarkers; Immunohistochemistry; Tissue microarrays;

    Sammanfattning : AbstractBackground: Adenocarcinomas arising in the area around the papilla of Vater are referred to as periampullary adenocarcinomas and are of four different anatomical origins: pancreas, distal bile duct, ampulla and duodenum. These heterogeneous tumors are usually divided into two morphological subtypes, pancreatobiliary type (PB-type) and intestinal type (I-type), which provides more important prognostic information than tumor origin. LÄS MER

  4. 18. In search of early biomarkers in pancreatic ductal adenocarcinoma using multi-omics and bioinformatics

    Författare :Emmy Borgmästars; Malin Sund; Ola Billing; Pär Jonsson; Zelmina Lubovac-Pilav; Oskar Franklin; Stefan Enroth; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pancreatic cancer; microRNA functional analysis; TPS; miRNomics; metabolomics; proteomics; plasma samples; early detection; risk; survival;

    Sammanfattning : Background: Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive malignancy with a 5-year survival of 10 %. Surgery is the only curative treatment. Unfortunately, few patients are eligible for surgery due to late detection. Thus, we need ways to detect the disease at an earlier stage and for that good screening biomarkers could be used. LÄS MER

  5. 19. Prognostic factors in periampullary adenocarcinoma. A retrospective study over an 11 year period

    Författare :Jacob Elebro; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periampullary adenocarcinoma; Pancreatic cancer; bile duct cancer; ampullary adenocarcinoma; duodenal adenocarcinoma; Immunohistochemestry; prognosis;

    Sammanfattning : Periampullary adenocarcinoma, including pancreatic cancer, has a poor prognosis that has not improved in the last decades. Therefore, in order to find more effective treatment regimens, it is necessary to gain more insight into the biology and clinical behaviour of these tumours. LÄS MER

  7. 20. Basement membrane collagens in pancreatic cancer : novel stroma-derived tumor markers and regulators of cancer cell growth

    Författare :Daniel Öhlund; Malin Sund; Peter Naredi; Matthias Löhr; Umeå universitet; []
    Nyckelord :Pancreatic cancer; tumor marker; basement membrane; type IV collagen; type XVIII collagen; matrix metalloproteinase; integrin; autocrine loop; tumor stroma; kirurgi; Surgery;

    Sammanfattning : Background: Among the common malignancies, pancreatic cancer has the shortest long-term survival. The aggressive, rapid, and infiltrative growth pattern of pancreatic cancer, together with the lack of specific symptoms, often leads to late diagnosis. LÄS MER