Sökning: "PTPA"

Hittade 2 avhandlingar innehållade ordet PTPA.

1. 1. Structural Studies on PP2A and Methods in Protein Production

   Författare :Auður Magnúsdóttir; Pär Nordlund; Herman Van Tilbeurgh; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PP2A; PTPA; B56γ; Protein Production; Structural biology; Strukturbiologi; biokemi; Biochemistry;

   Sammanfattning : PP2A is a major phosphatase in the cell that participates in multiple cell signaling pathways. It is a heterotrimer of a core dimer and variable regulatory subunits. Details of its structure, function and regulation are slowly emerging. Here, the structure of two regulators of PP2A are de-scribed; PTPA and B56γ. LÄS MER

3. 2. Structural studies of three cell signaling proteins : crystal structures of EphB1, PTPA, and YegS

   Författare :Amin Bakali; Pär Nordlund; Wenqing Xu; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein production; structural genomics; cell signaling; Biochemistry; Biokemi;

   Sammanfattning : Kinases and phosphatases are key regulatory proteins in the cell. The disruption of their activities leads ultimately to the abolishment of the homeostasis of the cell, and is frequently correlated with cancer. EphB1 is a member of the largest family of receptor tyrosine kinases. It is associated with neurogenesis, angiogenesis, and cancer. LÄS MER