Sökning: "PTB"

Visar resultat 16 - 20 av 23 avhandlingar innehållade ordet PTB.

1. 16. Mediators of cervical ripening in preterm birth : experimental and clinical investigations

   Författare :Susanne Abelin Törnblom; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cervix; preterm; cervical ripening; cytokines; chemokines; cyclooxygenase COX ; prostaglandin dehydrogenase PGDH ; induction; labour; nitric oxide; PgE2-gel; pregnancy; preterm labour;

   Sammanfattning : Background: Preterm birth (PTB) is by far the leading worldwide cause of infant mortality and morbidity. Despite decades of research, the frequency of PTB has not decreased and the basic mechanisms initiating the onset of labour are still poorly understood. Vaginal preterm birth cannot take place without cervical softening and remodelling. LÄS MER

3. 17. Regulation of RNA Processing in Human Papillomavirus Type 16

   Författare :Margaret Rush; Stefan Schwartz; Jörgen Kjems; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; RNA processing; human papillomavirus; HPV-16; alternative splicing; polyadenylation; exonic splicing enhancer; 3 UTR; upstream polyadenylation element; SR proteins; Molekylärbiologi; Molecular biology; Molekylärbiologi;

   Sammanfattning : Human papillomavirus type 16 (HPV-16) is the major cause of cervical cancer. HPV-16 gene expression is tightly linked to the differentiation programme of the infected epithelium. Expression of the late genes, L1 and L2, encoding the capsid proteins, is delayed until the more terminally differentiated cells. LÄS MER

4. 18. Bio-inspired crossover and a model of neuronal reprogramming

   Författare :Adriaan Merlevede; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary comuptation; crossover; genetic recombination; permutation; flexible genome; direct neuronal reprogramming;

   Sammanfattning : Bio-inspired crossover:Natural genomes are affected by various kinds of mutations, manifesting as variations in the genome. This includes modifications to individual base pairs (single nucleotide polymorphism, SNP), but also short insertions and deletions (indels), and variations in the position (translocations) or multiplicity (copy number variations) of genetic sequences. LÄS MER

5. 19. Vaginal commensal bacteria. Interactions with cervix epithelial and monocytic cells and influence on cytokines and secretory leukocyte protease inhibitor, SLPI

   Författare :Louise Strömbeck; Göteborgs universitet; []
   Nyckelord :Prevotella bivia; bacterial vaginosis BV ; invasion; Lactobacillus; secretory leukocyte protease inhibitor SLPI ; cytokines; THP-1; HeLa cells;

   Sammanfattning : Vaginal commensal bacteria Interactions with cervix epithelial and monocytic cells and influence on cytokines and secretory leukocyte protease inhibitor, SLPI Louise Strömbeck Department of Infectious Medicine, Gothenburg University Abstract Lactobacillus is the predominant species of the vaginal microbiota in women of childbearing age. Lactobacilli are thought to contribute to the local immune defence by producing a variety of antimicrobial substances and, thereby, attenuate growth of other opportunistic bacteria. LÄS MER

7. 20. Regulation of Human Papillomavirus Type 16 mRNA Splicing and Polyadenylation

   Författare :Xiaomin Zhao; Stefan Schwartz; Barklie Clements; Uppsala universitet; []
   Nyckelord :Medical sciences; human papillomavirus type 16; gene regulation; splicing; polyadenylation; 3 UTR; MEDICIN OCH VÅRD; MEDICINE; MEDICIN;

   Sammanfattning : Human papillomavirus type 16 (HPV-16) is the major causative agent of cervical cancer. The life cycle of this oncogenic DNA tumour virus is strictly associated with the differentiation program of the infected epithelial cells. Expression of the viral capsid genes L1 and L2 can only be detected in the terminally differentiated epithelial cells. LÄS MER