Sökning: "PSC"

Visar resultat 21 - 25 av 48 avhandlingar innehållade ordet PSC.

  1. 21. The importance of fat and alcohol for progression and prognosis in chronic liver disease

    Författare :Hannes Hagström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic liver disease is an increasing cause of global morbidity and mortality. The popular belief is that liver disease is caused mainly by alcoholic liver disease or viral hepatitis. LÄS MER

  2. 22. Inflammatory bowel disease : risk factors for adverse outcomes, and preventive measures

    Författare :Dan Kornfeld; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The purpose of this thesis was to identify risk factors for malignant transformation, survival, pregnancy outcomes and complications Further to assess the impact of surveillance colonoscopy and pharmacotherapy as a preventive measures in patients inflammatory bowel disease (IBD). As sources of information we have utilized following population based cohorts3112 patients with ulcerative colitis diagnosis within the Uppsala Health Care Region from 1965 to 1983, 125 patients with primary sclerosing cholangitis collected from7 different hospitals in central of Sweden from 1964 to 1991, 239773 single births in Sweden from 1991 to 1992 and 4664 patients with ulcerative colitis diagnosis within the Uppsala Health Care Region and Stockholm County between year 1955 to 1984. LÄS MER

  3. 23. Analysis of stratospheric ozone depletion in the Arctic using a data assimilation technique

    Författare :Kazutoshi Sagi; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; data assimilation; ozone loss; limb sounding; remote sensing; stratosphere;

    Sammanfattning : Serious ozone depletion has been measured every Antarctic spring since the early 80’s. This ozone depletion is considered to be a result of photo chemical reactions and cat- alytic cycles resulting from anthropogenic halogen containing gases. LÄS MER

  4. 24. Circumventing drug resistance : Studies exploring the expediency of a total cell kill chemoresistance assay

    Författare :Bertil Jonsson; Uppsala universitet; []
    Nyckelord :Medical sciences; drug resistance; drug resistance assay; clinical correlations; cancer; human; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : Cellular resistance to anti-cancer drugs is considered to be the major cause of treatment failure in clinical practice. The present studies have therefore focused on ways to circumvent resistance as evaluated by an in vitro chemoresistance assay. LÄS MER

  5. 25. Image-based dynamic liver testing : studies of segmental hepatic parenchymal function and biliary flow using dynamic 99Tcm-HIDA SPECT

    Författare :Eduard Jonas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dynamic SPECT; Segmental liver function test; Primary sclerosing cholangitis; Bile flow; Bile scintigraphy;

    Sammanfattning : The aim of the study was to create a dynamic liver function test using a tomographic imaging procedure as sampling method. The liver has multiple and complex functions. It is obvious that no single test can give a comprehensive measurement of total liver function. LÄS MER