Sökning: "PSA"

Visar resultat 6 - 10 av 153 avhandlingar innehållade ordet PSA.

1. 6. Strategies for Miniaturized Biomarker Detection

   Författare :Belinda Adler; Avdelningen för Biomedicinsk teknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomarker; miniturization; lab-on-a-chip; proteomics; PSA; microarray; mass spectrometry; MALDI MS; SPE; sample preparation; immunoaffinity; antibody; aptamer; mass tag; ISET.;

   Sammanfattning : The aim of this thesis is development and application of different miniaturized strategies for detection of biomarkers. The biomarker PSA (prostate specific antigen), which is prostate cancer specific, has been the main focus of the thesis. LÄS MER

3. 7. Human Glandular Kallikrein 2

   Författare :Janita Lövgren; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; seminal plasma; semenogelin; PCI; serpin; zinc; cancer; prostate; PSA; hK2; serine protease; kallikrein; Clinical chemistry; Klinisk kemi;

   Sammanfattning : Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in seminal plasma at mean levels of 6 mg/ml. It has 79% amino acid sequence identity with prostate-specific antigen (PSA or hK3). LÄS MER

4. 8. Translational and functional analyses of microRNAs in prostate cancer

   Författare :Olivia Larne; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; microRNA; PSA; androgen receptor; miR-96; miR-145; miR-183;

   Sammanfattning : The aims of this thesis were to identify microRNAs (miRNAs) with prostate cancer prognostic and diagnostic potential, to discover miRNAs with therapeutic capacity against prostate cancer, and to investigate if prostate specific antigen (PSA) is miRNA regulated. Prostate cancer is a globally spread disease with low mortality, but some patients develop an aggressive lethal form of prostate cancer with severe morbidity. LÄS MER

5. 9. Image analysis of prostate cancer tissue biomarkers

   Författare :Giuseppe Lippolis; Malmö Urologisk cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; image analysis; Time Resolved Fluorescence; automated Gleason; PSA; AR; fusion gene; TMAs;

   Sammanfattning : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. LÄS MER

7. 10. Real-time PCR and its application for protein quantification

   Författare :Kristina Lind; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ELISA; real-time immuno-PCR; real-time PCR; melt curve analysis; PSA; 3’UTR; TAP-tag; BOXTO; immuno-qPCR;

   Sammanfattning : The ability to quantify specific DNA sequences with real-time PCR has increased the possibilities for sensitive DNA analysis enormously. This sensitive technique can in optimal conditions detect one DNA copy and has a large quantification range. LÄS MER