Sökning: "PR-B"

Hittade 5 avhandlingar innehållade ordet PR-B.

  1. 1. Effects of mifepristone on the human endometrium and the fallopian tube during the luteal phase

    Författare :Xiaoxi Sun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mifepristone; endometrial receptivity; emergency contraception; PR-B; eNOS; IGFBP-1; PRL; HB-EGF; HB-EGF receptors HER1 and HER4;

    Sammanfattning : Mifepristone given postovulatory has been shown effective for contraception, but the precise mechanism of action is still poorly understood. A better understanding of the mechanisms of action of mifepristone, when used for contraception, is important for further development and optimizing the regimen of use. LÄS MER

  3. 2. Levonorgestrel emergency contraception : effects on endometrial development and embryo implantation

    Författare :Chun-Xia Meng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Emergency contraception; levonorgestrel; endometrial receptivity markers; embryo implantation; first-trimester tissues;

    Sammanfattning : Background: The dialog between the developing embryo and receptive endometrium is under the control of ovarian steroids and numerous biomolecules, some of which have been suggested as markers of endometrial receptivity. Unintended pregnancies are common. The standard treatment with levonorgestrel (LNG, 1. LÄS MER

  4. 3. Studies on the extracellular matrix of the dysfunctional pelvic floor

    Författare :Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

    Sammanfattning : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. LÄS MER

  5. 4. Intraovarian mechanisms influencing the human corpus luteum

    Författare :Ulrika Ottander; Torbjörn Hillensjö; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Corpus luteum; steroidreceptors; progesterone; LH hCG; PGF2α; ultrasonography;

    Sammanfattning : Introduction: The human corpus luteum (CL) is a transient endocrine gland, only functionally active for about 14 days. Its principal function is to produce and secrete progesterone and thereby support the endometrium for implantation of a blastocyst and prevent rejection of the developing embryo. LÄS MER

  7. 5. Endometrial receptivity and human embryo implantation : in vivo and in vitro studies

    Författare :Sujata Lalit Kumar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :3D-endometrial cell construct;

    Sammanfattning : Background: Infertility, one of the common gynaecological disorders, affects 10-15% women in their reproductive years. Despite the advances in assisted reproduction techniques and the best efforts of infertility specialists, implantation rates do not exceed more than 28-30%. LÄS MER