Hittade 2 avhandlingar innehållade ordet PNPLA.
Sammanfattning : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. LÄS MER
Sammanfattning : Lipids - including fatty acids (FAs), triglycerides (TGs), cholesterol and cholesterol esters (CEs) - are hydrophobic molecules involved in several important structural and mechanistic processes. Lipids are found in cellular membranes, give posture and stability to the cell, are actively participating in cellular signaling, and act as mediators in several important biological pathways. LÄS MER