Sökning: "PMNs"
Visar resultat 1 - 5 av 24 avhandlingar innehållade ordet PMNs.
1. Persistent infection by Yersinia pseudotuberculosis
Sammanfattning : Enteropathogenic Yersinia species can infect many mammalian organs such as the small intestine, cecum, Peyer’s patches, liver, spleen, and lung and cause diseases that resemble a typhoid-like syndrome, as seen for other enteropathogens. We found that sublethal infection doses of Y. LÄS MER
2. Apoptotic neutrophils enhance the immune response against Mycobacterium tuberculosis
Sammanfattning : Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a disease that for years was considered to belong of the past, but tuberculosis is back causing over 2 million deaths per year. The infection can be dormant for decades and an active immune response can prevent the infection from progressing into active disease. LÄS MER
3. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide
Sammanfattning : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. LÄS MER
4. Yersinia-phagocyte interactions during early infection
Sammanfattning : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. LÄS MER
5. Mechanisms of inflammatory lung injury : Studies in isolated perfused rat lungs
Sammanfattning : Isolated perfused rat lungs (IPRLs) were used to study mechanisms andmediators of lung injury due to (i) ischemia-reperfusion (IR) and (ii) endotoxin. To investigate the role of polymorphonuclear neutrophils (PMNs) in IR injury, PMNs were added to the perfusate of IPRLs subjected to IR. LÄS MER