Sökning: "PML"
Visar resultat 1 - 5 av 31 avhandlingar innehållade ordet PML.
1. TRIM22/Staf50 - a novel target gene of the tumor suppressor p53
Sammanfattning : The tumor suppressor gene p53 is a transcription factor that mediates cell cycle arrest, apoptosis and differentiation. p53 mediated differentiation of leukemic cells depends on the transcriptional activity of p53 but so far no obvious differentiation inducing target gene has been identified. LÄS MER
2. Direct and Inverse Methods for Waveguides and Scattering Problems in the Time Domain
Sammanfattning : Numerical simulation is an important tool in understanding the electromagnetic field and how it interacts with the environment. Different topics for time-domain finite-difference (FDTD) and finite-element (FETD) methods for Maxwell's equations are treated in this thesis. LÄS MER
3. Absorbing Layers and Non-Reflecting Boundary Conditions for Wave Propagation Problems
Sammanfattning : The presence of wave motion is the defining feature in many fields of application,such as electro-magnetics, seismics, acoustics, aerodynamics,oceanography and optics. In these fields, accurate numerical simulation of wave phenomena is important for the enhanced understanding of basic phenomenon, but also in design and development of various engineering applications. LÄS MER
4. Nuclear compartmentalization of viral and cellular proteins involved in gamma-herpes virus (EBV and HHV-8) mediated cellular transformation
Sammanfattning : The aim of the work described in this thesis has been to characterize the nuclear compartmentalization of cellular and viral proteins involved in EBV or HHV-8 mediated cellular transformation. We have studied the EBV encoded EBNA-5 and its association with the PML nuclear bodies (NBs) and nuclear inclusions. LÄS MER
5. Topographical study of intranuclear distribution and compartementalization of viral and cellular proteins
Sammanfattning : The nuclei of eukaryotic cells contain a number of specialized domains involved in DNA replication, transcription, pre-mRNA splicing and ribosome assembly. In addition to these structures, nuclear bodies of unknown function have been described. LÄS MER