Sökning: "PLP"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet PLP.

1. 1. Biocatalytic transamination with recombinant Saccharomyces cerevisiae: Challenges and opportunities

   Författare :Nora Weber; Teknisk mikrobiologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; transamination; whole-cell biocatalysis; pyruvate; PLP; thiamine; reduction;

   Sammanfattning : Chiral building blocks are important molecules for synthesis of fine chemicals and pharmaceuticals. Biocatalysis has gained in relevance over traditional organic methods for synthesis of chiral compounds, as reactions can be performed at high enantio-selectivity and purity with environmentally friendly, simple, and cheap methods. LÄS MER

3. 2. Transaminase Biocatalysis: Applications and Fundamental Studies

   Författare :Federica Ruggieri; Per Berglund; Mariarita Bertoldi; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biocatalysis; enzymatic cascade; transaminase; amine; racemization; PLP; enzyme engineering; Chromobacterium violaceum; protein stability; enzyme stability; molecular dynamics; structural biology; enzyme technology; chiral amines; kinetic resolution; Bioteknologi; Biotechnology;

   Sammanfattning : Biocatalysis is the branch of science at the intersection between chemistry and biology and specifcally dedicated to the application of natural evolvable catalysts, i.e. enzymes, in human-designed chemical processes. Among the array of promising biocatalysts, transaminases (EC 2. LÄS MER

4. 3. Investigating Phantom Motor Execution as treatment of Phantom Limb Pain

   Författare :Eva Lendaro; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Randomized Controlled Trial; Phantom Limb Sensations; Phantom Limb Pain; EEG.; Phantom Motor Execution; Amputation;

   Sammanfattning : Phantom Limb Pain (PLP) is commonly suffered by people with amputations and even though it has been studied for centuries, it remains a mysterious object of debate among researchers. For one thing, despite the vast number of proposed PLP treatments, no therapy has so far proved to be reliably effective. LÄS MER

5. 4. On the use of Phantom Motor Execution for the treatment of Phantom Limb Pain

   Författare :Eva Lendaro; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amputation; Randomized Controlled Clinical Trial.; Phantom Limb Sensations; Phantom Limb Pain; Phantom Motor Execution;

   Sammanfattning : Phantom limb pain (PLP) is a common complaint among amputees and despite having been studied for centuries, it remains a mysterious object of debate among researcher. To date, a vast number of ways to treat PLP has been proposed in the literature, however none of them has proven to be universally effective, thus creating uncertainty on how to operate clinically. LÄS MER

7. 5. Stability and inactivation mechanisms of two transaminases

   Författare :Shan Chen; Per Berglund; Patrick Adlercreutz; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Amine Transaminase; Operational Stability; Inactivation Pathway; Enzyme Unfolding; Phosphate Group Binding Cup; Bioteknologi; Biotechnology;

   Sammanfattning : In the past decades, more and more enzymes are employed as biocatalysts in industrial processes because of their advantages, such as high efficiency, substrate selectivity and stereoselectivity. Among them, amine transaminases (ATAs) are pyridoxal 5’-phosphate (PLP) dependent enzymes. LÄS MER