Sökning: "PD-L1"
Visar resultat 21 - 25 av 45 avhandlingar innehållade ordet PD-L1.
21. Genetics of diffuse large B-cell lymphoma
Sammanfattning : Diffuse large B-cell lymphoma (DLBCL) is one the most common forms of non-Hodgkin lymphoma and one of the most aggressive B-cell neoplasms. Although most patients respond to current standard treatments, a significant number of them relapse and become refractory to treatment. Hence, there is a need for new approaches in the management of DLBCL. LÄS MER
22. Strategies to optimize natural killer cell functions in the tumor microenvironment
Sammanfattning : Immune cell-based therapies are currently changing the oncological treatment landscape worldwide. While genetically modified T cells have already been approved for clinical use in few hematological cancers, natural killer (NK) cell-based therapies are employed in early phase clinical trials. LÄS MER
23. Immune response and tumour cell detection in lymph nodes of head and neck cancer
Sammanfattning : Many patients with head and neck squamous cell carcinoma present with regional spread to the cervical lymph nodes. Lymph nodes metastases are today the most important factor influencing both the treatment and outcome for this type of cancer. LÄS MER
24. Pathophysiological role and therapeutic potential of extracellular vesicles in cancer
Sammanfattning : Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are endogenously generated through various biogenesis pathways within most cellular entities. Subsequently, they are released into the extracellular milieu to facilitate intercellular communication. LÄS MER
25. Decoding the tumor microenvironment : a B-cell and macrophage perspective
Sammanfattning : The immune system plays a role in many different functions in our body, and disease is no exception. Cancer is one of the biggest challenges of the twenty first century and vast efforts have been made to understand this disease. LÄS MER