Sökning: "PCR inhibition mechanisms"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden PCR inhibition mechanisms.
1. PCR inhibition mechanisms in forensic DNA analysis
Sammanfattning : In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. LÄS MER
2. Leukocyte sequestration associated with inflammation : mechanisms and modulations
Sammanfattning : Inflammationsreaktionen är kroppens första försvar mot främmande partiklar t ex bakterier. Det är en komplex reaktion som bl a karakteriseras av att vita blodkroppar dras till det inflammerade området och att vätskao i blodet lättare tar sig igenom kärlväggen till vävnaden dvs det svullnar. LÄS MER
3. Optimisation of diagnostic PCR a study of PCR inhibitors in blood and sample pretreatment
Sammanfattning : PCR is widely employed as a rapid, sensitive and specific molecular diagnostic technique in clinical diagnosis, environmental investigations and for monitoring biotechnical processes. However, the full potential of diagnostic PCR is limited, in part, by the presence of PCR-inhibitory substances in biological samples. LÄS MER
4. Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa
Sammanfattning : Pseudomonas aeruginosa is an opportunistic nosocomial pathogen. In compromised human, it can cause infections in urinary tract, wound and respiratory tract such as pneumonia and progressive lung diseases. LÄS MER
5. Mechanisms of p53-mediated intrinsic and extrinsic tumor suppression
Sammanfattning : p53 is a promising target for cancer therapy. However, the molecular basis of the p53 tumor suppression function remains incompletely understood. Thus, in this thesis, we focused on studies of the molecular mechanisms of p53-mediated tumor suppression. LÄS MER