Sökning: "PAMPS"

Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet PAMPS.

  1. 6. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

    Författare :Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

    Sammanfattning : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. LÄS MER

  3. 7. Structural and functional studies of class A scavenger receptors MARCO (SCARA2) and SCARA5

    Författare :Juha Ojala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our bodies are constantly exposed to various microorganisms and there is a constant battle between their survival and ours. Fortunately we are equipped with our immune system that takes remarkably good care of us, but when it fails we all know the consequences. LÄS MER

  4. 8. Toll-like receptors in airway inflammation in vitro and in vivo

    Författare :Ida von Schéele; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During evolution a variety of solutions has been developed by different living organisms in order to protect itself from invading potential pathogens and particles. Protection of the host is essential for its survival and involves efficient recognition and elimination of potential pathogens. LÄS MER

  5. 9. Modulation of neutrophil extracellular trap formation in health and disease

    Författare :Ava Hosseinzadeh; Constantin F. Urban; Carol Munro; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Candida albicans; Adenosine; Tempol; Nicotine; molekylärbiologi; Molecular Biology;

    Sammanfattning : The critical prompt innate immune response is highly built upon the influx of neutrophils from the blood stream to the site of infection. In the battlefield, neutrophils sense pathogen-associated molecular patterns (PAMPs) through their pattern-recognition receptors (PRRs) to launch a number of responses with the goal to defeat the invading pathogen. LÄS MER