Sökning: "PAMAM"

Hittade 4 avhandlingar innehållade ordet PAMAM.

  1. 1. Nanostructured surfaces created by the interactions of dendrimers and oppositely charged amphiphiles

    Detta är en avhandling från Division of Physical Chemistry, Faculty of Science, Lund University

    Författare :Marianna Yanez; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAMAM; Surfactant; SDS; Lipid; Bilayer; Model Biomembrane; Nucleolipid; DLPA; DLPU; DNA; RNA; Neutron Reflectometry; Poly amidoamine ; Interface; Adsorption; Polyelectrolyte;

    Sammanfattning : The research described in this thesis aims to understand the interactions between cationic poly(amidoamine) (PAMAM) dendrimers and small oppositely charged amphiphiles at the solid-liquid and air-liquid interfaces in relation to the bulk solution behavior. There is high interest in PAMAM dendrimers because they are well-defined polymers with a hierarchical architecture which makes them promising materials as nanocapsules and gene vectors. LÄS MER

  2. 2. Controlling DNA compaction and the interaction with model biomembranes

    Detta är en avhandling från Division of Physical Chemistry, Faculty of Science, Lund University

    Författare :Marie-Louise Ainalem; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; model biomembrane; DNA compaction; cryo-TEM; null ellipsometry; dynamic light scattering; toroid; bilayer; neutron reflectivity; dendrimer; PAMAM; DNA; poly amido amine ;

    Sammanfattning : The studies described in this thesis forms part of a larger collaborative project, Neonuclei, with the objective to design a module for packaging the negatively charged DNA into a ”neonucleus” with transcription competence. There are many applications that require control of DNA compaction, i.e. packaging or condensation. LÄS MER

  3. 3. Dendrimer-mediated gene delivery: Effect of polymer structure on cellular response

    Detta är en avhandling från Division of Physical Chemistry, Faculty of Science, Lund University

    Författare :Kristina Fant; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene therapy; DNA condensation; cationic polymers; toxicity; non-viral vector; drug delivery; polyplex; PAMAM dendrimers;

    Sammanfattning : The delivery of nucleic acids to cells, in vitro and in vivo, is becoming a realistic approach for intervention with gene expression at a molecular level. It can be used to repair malfunctioning genes or to introduce new functionalities, with the most important application being clinical treatment of human diseases. LÄS MER

  4. 4. Engineered nanomaterials for biomedical applications

    Detta är en avhandling från Stockholm : Karolinska Institutet, Institute of Environmental Medicine

    Författare :Neus Feliu Torres; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Engineered nanomaterials (ENM) have emerged as attractive and promising candidates for a wide range of advanced applications including in particular in medicine. However, the increased development of ENM raises the need to carefully assess their potential impact on human health and environment. LÄS MER