Sökning: "PAE"

Visar resultat 1 - 5 av 33 avhandlingar innehållade ordet PAE.

1. 1. Antibiotics in patients on chemotherapy; aspects on pharmacokinetic and pharmacodynamic interactions with antineoplastic drugs

   Författare :Anna Nyhlén; Sektion III; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotics; neutropenic; antineoplastic agents; pharmacokinetics; pharmacodynamics; PAE; interactions; synergy; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; mykologi; virologi;

   Sammanfattning : The aims of these studies were to investigate the pharmacokinetics of two beta-lactam antibiotics in patients with fever and cytostatic-induced neutropenia and the influence of cytostatic-induced gastrointestinal damage on the absorption of co-trimoxazole. Furthermore to study the pharmacodynamic interactions between antibiotics and antineoplastic drugs and the impact of antineoplastic drugs on the intestinal microflora. LÄS MER

3. 2. Pre-analytical errors in blood sampling procedures in paediatric hospital care

   Författare :Henrik Hjelmgren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Introduction: Blood tests are important for diagnosing and treating children who are hospitalised with illnesses. The blood test process follows the specific phases of pre-analysis, analysis and post-analysis. Most blood test errors occur in the pre-analytical phase. LÄS MER

4. 3. Pharmacodynamic effects of antibiotics on growing and nongrowing bacteria

   Författare :Erik Svensson; Peter Larsson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The main objective of this thesis was to study antibiotic effects on nongrowing baCteria and to study the development of resistance in Staphylococcus epidermidis, a bacterium which is often found in biofilm infections. The antibiotic effect on biofilm infections is generally weak, which probably is due to decreased growth rate of the bacteria. LÄS MER

5. 4. Polyelectrolyte adsorption on oppositely charged surfaces - Conformation and adsorption kinetics

   Författare :Lars-Erik Enarsson; Lars Wågberg; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polyelectrolyte adsorption; adsorption kinetics; adsorption isotherms; conformation; bridging; stagnation point adsorption reflectometry; quartz crystal microgravimetry; polyelectrolyte titration; cationic polyacrylamide; cationic dextran; colloidal silica; silica surfaces; pulp; Chemistry; Kemi;

   Sammanfattning : Denna avhandling presenterar experimentella studier av polyelektrolytadsorption på motsatt laddade ytor, där substrat av både kiseloxid och blekt barrsulfatmassa har använts. Ett huvudsakligt syfte med denna forskning var att karaktärisera konformationen hos adsorberade skikt av katjonisk polyakrylamid (CPAM) i jämförelse med katjonisk dextran (Cdextran) och relatera denna information till inbindningskapaciteten av kolloidal kiselsyra. LÄS MER

7. 5. Treatment of helicobacter pylori infection : experimental and clinical studies

   Författare :Mikael Sörberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Helicobacter pylori; coccoid form; treatment; pharmacodynamics; resistance; serology Stockholm 1997;

   Sammanfattning : The general aims of the present study were to investigate the reason for failed H. pylori eradication, and to improve the recommendations for treating H. pylori infection. Our in vitro studies are based on microscopy, viable count and bioluminescence assay of bacterial adenosine triphosphate (ATP). LÄS MER