Sökning: "PAD4"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet PAD4.

  1. 1. On the Mechanism of Neutrophil Extracellular Traps in Acute Pancreatitis

    Författare :Raed Madhi; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; chemokines; neutrophil recruitment; PAD4; c-Abl kinase; NETs; NET-MPs complexes;

    Sammanfattning : .... LÄS MER

  3. 2. Genetic and Molecular Mechanisms Controlling Reactive Oxygen Species and Hormonal Signalling of Cell Death in Response to Environmental Stresses in Arabidopsis thaliana

    Författare :Per Mühlenbock; Stanislaw Karpinski; Barbara Karpinska; Pierre Frendo; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant physiology; Växtfysiologi;

    Sammanfattning : In the present work the regulation of environmentally induced cell death and signaling of systemic acquired acclimation (SAA) in Arabidopsis thaliana is characterized. We used the lesion simulating disease1 (lsd1) mutant as a model system that is deregulated in light acclimation and programmed cell death (PCD). LÄS MER

  4. 3. On Generation and Function of Neutrophil Extracellular Traps in Abdominal Sepsis

    Författare :Avin Hawez; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal sepsis; inflamation; neutrophil; neutrophil extracellular traps; mRNA; adhesion.;

    Sammanfattning : AbstractSepsis is a clinical condition that develops when the immune system over-response to an infection. Sepsis can lead to organ failure as well as subsequent death. Sepsis-induced host response involves neutrophil over activation which can lead to self tissue damage. LÄS MER

  5. 4. Studies on the relationship between periodontitis and rheumatoid arthritis

    Författare :Kaja Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Periodontitis and rheumatoid arthritis (RA) are both widespread multifactorial diseases, characterized by chronic inflammation leading to tissue and bone destruction around teeth or joints, respectively. An association between periodontitis and RA has been proposed, suggesting that the periodontal pathogen Porphyromonas gingivalis (P. LÄS MER

  7. 5. Arthritogenic and immunogenic properties of modified autoantigens

    Författare :Karin Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Post-translational modifications; pH; chlorination; citrullination; CII; CIA; RA;

    Sammanfattning : Rheumatoid arthritis is a chronic inflammatory joint disorder with autoimmune features in which both genetic and environmental factors are potential contributors to the arthritogenic process. In this thesis work we aimed to increase the understanding of early pathogenic events underlying the development of this complex disease by investigating the arthritogenic and immunogenic properties of modified autoantigens in experimental settings as well as in RA patients. LÄS MER