Sökning: "P2Y12 inhibitors"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden P2Y12 inhibitors.
1. Platelet Inhibition in Coronary Artery Disease – Mechanisms and Clinical Importance : Studies with Focus on P2Y12 Inhibition
Sammanfattning : Despite the currently recommended dual antiplatelet treatment (DAT) with aspirin and P2Y12 inhibition in patients with coronary artery disease (CAD) there is a risk of adverse clinical outcome. Pharmacodynamic (PD) poor response to clopidogrel occurs in ~ 30% of clopidogrel-treated patients and is associated with an increased risk of recurrent thrombotic events. LÄS MER
2. Novel Agonists and Antagonists of Platelet Receptors
Sammanfattning : Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. LÄS MER
3. Impact of chronic total occlusions, arterial access site, and pretreatment with antiplatelet drugs on mortality in patients with ischemic heart disease: A report from the SWEDEHEART registry
Sammanfattning : Impact of chronic total occlusions, arterial access site and pretreatment with antiplatelet drugs on mortality in patients with ischemic heart disease: A report from the SWEDEHEART registry Background Treatment of ischemic heart disease has advanced substantially in the past half-century. However, despite these achievements the survival rates in high-income countries such as Sweden have reached a plateau in the last decade. LÄS MER
4. Platelet Inhibition, Revascularization, and Risk Prediction in Non-ST-elevation Acute Coronary Syndromes
Sammanfattning : Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most common manifestation. Despite improved outcomes during the last decades, patients with acute coronary syndromes (ACS) are still at substantial risk of recurrent ischemic events and mortality. LÄS MER
5. Point-of-care testing of platelet P2Y12-inhibition in patients with acute coronary syndrome
Sammanfattning : Background: The point-of-care platelet function test Plateletworks® has been shown to identify patients with high platelet aggregation despite P2Y12 inhibition, also known as high-on-treatment platelet reactivity (HPR), who have increased risk for ischemic cardiovascular events. However, this platelet function assay has not been sufficiently validated. LÄS MER