Sökning: "P domain"

Visar resultat 11 - 15 av 186 avhandlingar innehållade orden P domain.

  1. 11. Rektorers normer i ledarskapet för skolutveckling

    Författare :Helena Hallerström; Rättssociologiska institutionen; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Social sciences; norm analyses; norm model; structures; norm supporting; norms; local authorities; law; decentralisation; steerage; principals´ domain; domain; principals´ norms; curriculum development; educational development; education; development; leadership; headmaster; Sociology of law; principal; Juridical science; Administrative law; Sociology; Samhällsvetenskaper; Rättsvetenskap; juridik; Förvaltningsrätt; Sociologi;

    Sammanfattning : This thesis puts a focus on school leadership and school development. The local authorities took over responsibility for public education in 1991. At the same time, steerage by rules was abandoned in favour of steerage by goal-setting and result evaluation. The principal is an important link in this chain of steerage. LÄS MER

  3. 12. Distal to Proximal—Functional Coupling in RNase P RNA-mediated Catalysis

    Författare :Shiying Wu; Leif A. Kirsebom; Britt-Marie Sjöber; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribozyme; RNase P; Induced fit model; tRNA progressing; Substrate interaction;

    Sammanfattning : RNase P is a ubiquitous ribonuclease responsible for removing the 5’ leader of tRNA precursor. Bacterial RNase P contains one RNA (RPR) and one protein (RPP) subunit. However, the number of protein variants depends on the origin. The RNA subunit is the catalytic subunit that in vitro cleaves its substrate with and without the protein subunit. LÄS MER

  4. 13. Studies of the Boundary Behaviour of Functions Related to Partial Differential Equations and Several Complex Variables

    Författare :Håkan Persson; Kaj Nyström; Maciej Klimek; Evgeny Poletsky; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; uniformly parabolic equations; non-linear parabolic equations; linear growth; Lipschitz domain; NTA-domain; Riesz measure; boundary behavior; boundary Harnack; degenerate parabolic; parabolic measure; plurisubharmonic functions; continuous boundary; hyperconvexity; bounded exhaustion function; Hölder for all exponents; log-lipschitz; boundary regularity; approximation; Mergelyan type approximation; plurisubharmonic functions on compacts; Jensen measures; monotone convergence; plurisubharmonic extension; plurisubharmonic boundary values; Mathematics; Matematik;

    Sammanfattning : This thesis consists of a comprehensive summary and six scientific papers dealing with the boundary behaviour of functions related to parabolic partial differential equations and several complex variables.Paper I concerns solutions to non-linear parabolic equations of linear growth. LÄS MER

  5. 14. Structural and biochemical basis for the high fidelity and processivity of DNA polymerase ε

    Författare :Rais Ahmad Ganai; Erik Johansson; Per Elias; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA polymerase ε; Crystal structure; P domain; Pre-steady state kinetics; β-hairpin loop; Primer switching; Strand displacement; biokemi; Biochemistry;

    Sammanfattning : DNA polymerase epsilon (Pol ε) is a multi-subunit B-family DNA polymerase that is involved in leading strand DNA replication in eukaryotes. DNA Pol ε in yeast consists of four subunits, Pol2, Dpb2, Dpb3, and Dpb4. Pol2 is the catalytic subunit and Dpb2, Dpb3, and Dpb4 are the accessory subunits. LÄS MER

  7. 15. Determining the effects of regulatory parameters on the structural dynamics of P-type ATPase membrane transporters

    Författare :Fredrik Orädd; Magnus Andersson; Magnus Wolf-Watz; Marco Cammarata; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein dynamics; regulation; time-resolved x-ray solution scattering; MD simulation; membrane protein; P-type ATPase; SERCA; CopA; HMA4; adenylate kinase; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Proteins are macromolecular machines with roles in all cellular activities and structures. The functional properties of each protein is the result of its combination of 3D-structure and inherent dynamics, and a wealth of structural and dynamic mechanisms have evolved to regulate protein activity. LÄS MER