Sökning: "P domain"

Visar resultat 1 - 5 av 495 avhandlingar innehållade orden P domain.

  1. 1. Optimization of time domain induced polarization data acquisition and spectral information content

    Författare :P.-I. Olsson; Lunds universitet.; Lund University.; [2016-02-16]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; induced polarization 1P ; DCIP; spectral information; Data quality; Signal Processing;

    Sammanfattning : The need for detailed subsurface information is increasing due to city expansion and infill projects as well as subsurface construction projects. One common method for acquiring this geo-information is the direct current resistivity and time domain induced polarization method (DCIP) that measures the electrical resistivity and chargeability of the subsurface. LÄS MER

  2. 2. WNT/FZD signaling : an odyssey from molecular pharmacology to brain (patho)physiology

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Physiology and Pharmacology

    Författare :Jacomijn P. Dijksterhuis; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The 19 members of the lipoglycoprotein family of WNTs interact with the highly conserved cysteine-rich domain (CRD) of ten members of the Frizzled (FZD1-10) family. The seven transmembrane-spanning surface receptors are listed as G protein-coupled receptors and are known to interact with heterotrimeric G proteins as well as the scaffolding protein disheveled. LÄS MER

  3. 3. The role of PDGFB in dermatofibrosarcoma protuberans and giant cell fibroblastoma

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Författare :Kevin P. O'Brien; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatofibrosarcoma protuberans; giant cell fibroblastoma; translocation; FISH; translocation breakpoint; fusion gene; oncogene; Platelet derived growth factor B-chain; collagen type I alpha 1; tumor formation; autocrine stimulation;

    Sammanfattning : Dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) are rare invasive tumors of the dermis. GCF is considered the juvenile form of DFSP. Both DFSP and GCF are characterized by the presence of chromosomal aberrations involving chromosomes 17 and 22. LÄS MER

  4. 4. The role of Notch signaling in cancer and metastasis

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Anders P Mutvei; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Notch signaling pathway is an evolutionary conserved cell-to-cell communication pathway that regulates many important aspects in the development and tissue homeostasis of multicellular animals. It operates in a wide range of cellular contexts and dysregulated Notch signaling has been linked to a number of diseases, including cancer. LÄS MER

  5. 5. NA transmembrane domain Amphiphilic drift to accommodate two functions

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Johan Nordholm; Stockholms universitet.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; influenza; IAV; neuraminidase; NA; transmembrane domain; TMD; secretory protein; ER-targeting sequence; ER-targeting sequence coding region; protein regulation; NS1; GALLEX; biokemi; Biochemistry;

    Sammanfattning : Neuraminidase (NA) is one of two major antigens on the surface of influenza A viruses. It is comprised of a single N-terminal transmembrane domain (TMD), a stalk domain, and a C-terminal enzymatic head domain that cleaves sialic acid, most notably to release new particles from the host cell surface. LÄS MER