Sökning: "P Simonsson"

Hittade 4 avhandlingar innehållade orden P Simonsson.

  1. 1. On the interactions of ions and odor molecules with nanomaterials in water and synthetic urine

    Författare :Isabelle Simonsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nanomaterials; Surface chemistry; Ion specific effects; MOF synthesis; Odor control; Adsorption; Synthetic urine;

    Sammanfattning : Towards the quest of finding materials to be used as adsorbents in real systems, it is crucial to understand the underlying adsorption processesfully. In many applications, adsorption occurs in biological fluids containing a vast range of ions, organic molecules, and biomolecules. LÄS MER

  3. 2. Pharmacokinetic drug-drug interactions in the management of malaria, HIV and tuberculosis

    Författare :Doaa Elsherbiny; Ulrika Simonsson; Mats Karlsson; Lars Ståhle; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Drug-drug interactions; Cytochrome P-450; Artemisinin antimalarials; Nevirapine; Lopinavir; Rifampicin; NONMEM; Farmakokinetik Farmakoterapi;

    Sammanfattning : Malaria, Human Immunodeficiency Virus (HIV) and tuberculosis (TB) are global health problems having their worst situation in sub-Saharan Africa. Consequently, concomitant use of antimalarial, antiretroviral and antitubercular drugs may be needed, resulting in a potential risk of drug-drug interactions. LÄS MER

  4. 3. Protein Acetylation – A Multifunctional Regulator of TGF-β Signaling

    Författare :Maria Simonsson; Johan Ericsson; Eva Grönroos; Marikki Laiho; Uppsala universitet; []
    Nyckelord :Cell biology; TGF-β; Acetylation; Deacetylation; Acetyltransferase; HDAC; Smad; Transcription; Cellbiologi; MEDICINE; MEDICIN;

    Sammanfattning : Transforming growth factor β (TGF-β) is a member of a large family of cytokines that regulate many crucial events in cells, including proliferation, differentiation, migration and apoptosis. Deregulated TGF-β signaling is associated with various forms of cancers and developmental disorders. LÄS MER

  5. 4. Pharmacokinetics and Pharmacodynamics of Oxycodone and Morphine with Emphasis on Blood-Brain Barrier Transport

    Författare :Emma Boström; Margareta Hammarlund-Udenaes; Ulrika Simonsson; Danny D Shen; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; pharmacokinetics; pharamcodynamics; blood-brain barrier; oxycodone; microdialysis; NONMEM; brain distribution; transport; Farmakokinetik Farmakoterapi;

    Sammanfattning : The pharmacokinetics and pharmacodynamics of oxycodone and morphine was investigated and related to the transport across the blood-brain barrier (BBB) in rats. The influence of a P-glycoprotein (P-gp) inhibitor on the plasma pharmacokinetics and pharmacodynamics of oxycodone was evaluated. LÄS MER