Sökning: "P Karlsson"
Visar resultat 16 - 20 av 47 avhandlingar innehållade orden P Karlsson.
16. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects
Sammanfattning : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. LÄS MER
17. Unstable coronary artery disease : non-invasive indicators of severity of coronary lesions and the effects of thrombolysis
Sammanfattning : Non-invasive indicators of severity of coronary lesions and the effects of thrombolysis were evaluated in 205 men, 38 to 70 years of age with unstable coronary aticty disease (CAD)- i.e. unstable angina or non-Q wave myocardial infarction - admitted to the coronary care units in nine hospitals. LÄS MER
18. Improved diagnosis and management of sepsis and bloodstream infection
Sammanfattning : Sepsis is a severe organ dysfunction triggered by infections, and a leading cause of hospitalization and death. Concurrent bloodstream infection (BSI) is common and around one third of sepsis patients have positive blood cultures. LÄS MER
19. Pharmacokinetic drug-drug interactions in the management of malaria, HIV and tuberculosis
Sammanfattning : Malaria, Human Immunodeficiency Virus (HIV) and tuberculosis (TB) are global health problems having their worst situation in sub-Saharan Africa. Consequently, concomitant use of antimalarial, antiretroviral and antitubercular drugs may be needed, resulting in a potential risk of drug-drug interactions. LÄS MER
20. Detection of Biomolecules: Syntheses and Studies of Minor Groove Binding Unsymmetrical Cyanine Dyes and Chromogenic Enzyme Substrates
Sammanfattning : Visualisation or detection of biomolecules is usually achieved by the use of fluorescent or highly coloured chromophores. The work presented in this thesis deals with the development of new chromogenic substrates for the detection of enzyme activity, and new DNA-binding fluorescent dyes for staining of DNA. LÄS MER