Sökning: "Overexpression"
Visar resultat 16 - 20 av 602 avhandlingar innehållade ordet Overexpression.
16. Biochemical and Physiological Characterization of Nonsymbiotic Plant Hemoglobins
Sammanfattning : Hemoglobins (Hb) are usually associated with blood in humans. However, these proteins are widely distributed among living organisms. In plants the most known group are the leghemoglobins. Still, other Hbs that not participate in symbiosis are also found. LÄS MER
17. Cardiovascular, behavioural and metabolic consequences of growth hormone overexpression in transgenic mice
Sammanfattning : Growth hormone (GH) exerts major effects on body growth and metabolism. GH is also important in controlling cardiovascular function and behaviour. To study the role of growth hormone in cardiovascular function and regulation of blood pressure, we overexpressed bovine growth hormone regulated by the metallothionein promoter in mice (Mt-bGH). LÄS MER
18. The fruit fly Drosophila melanogaster GSTE6 and E7; characterization, immobilization and transgenic overexpression
Sammanfattning : Glutathione transferases (GSTs) are multifunctional enzymes that are universally distributed in most eukaryotes and prokaryotes. They play a pivotal role in the metabolism and detoxication of numerous endogenous and exogenous electrophiles by conjugating them with ubiquitous tripeptide glutathione. LÄS MER
19. In vitro Studies of β-cell Death and Survival. Modulation by Adenoviral Vectors and Bcl-2 Overexpression
Sammanfattning : Type 1 diabetes is a multifactorial disease resulting from the selective destruction of insulin-producing β-cells within the pancreatic islets of Langerhans. The mechanisms of β-cell death are not fully understood but cytokines are important mediators of this process. LÄS MER
20. Prognostic factors in squamous cell carcinoma of the head and neck, with emphasis on 11q13 rearrangements and cyclin D1 overexpression
Sammanfattning : At present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. LÄS MER