Sökning: "Overexpression"
Visar resultat 11 - 15 av 602 avhandlingar innehållade ordet Overexpression.
11. Neurothrophins during development : overexpression in neural stem cells
Sammanfattning : The neurotrophins constitute a family of secreted, diffusible peptide factors that are widely expressed in the developing nervous system. They are known to function as survival factors in the peripheral nervous system during the period of naturally occurring cell death, to promote axonal outgrowth and to affect neurotransmitter expression of responsive cells. LÄS MER
12. Novel Technologies for Recombinant Protein Overexpression in Escherichia coli
Sammanfattning : The use of recombinant protein is a cornerstone in many structural and functional studies. The enteric bacterium Escherichia Coli is the most commonly used organism for producing recombinant proteins. E. LÄS MER
13. From Biogenesis to Overexpression of Membrane Proteins in Escherichia coli
Sammanfattning : In both pro- and eukaryotes 20-30% of all genes encode alpha-helical transmembrane domain proteins, which act in various and often essential capacities. Notably, membrane proteins play key roles in disease and they constitute more than half of all known drug targets. LÄS MER
14. Cellular Resilience and Fragility in Response to Environmental and Gene Expression Perturbations
Sammanfattning : Cells are constantly subjected to perturbations. Whether these are extracellular or intracellular, they can be detrimental to cellular fitness. The cell has evolved elaborate systems and mechanisms that allow it to remain functional in the face of disturbances. LÄS MER
15. Cyclin E overexpression and associated events in human breast cancer
Sammanfattning : Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation and the pRb pathway occur frequently. Proliferation control can be circumvented either by excess cyclin D1 or cyclin E, alterations that can define two alternative tumour biologic pathways in breast cancer. LÄS MER
