Sökning: "Orphan"

Visar resultat 1 - 5 av 66 avhandlingar innehållade ordet Orphan.

  1. 1. The orphan : tragic form in Thomas Otway

    Författare :Kerstin Lund-Baer; Uppsala universitet; []
    Nyckelord :HUMANITIES; HUMANIORA; HUMANIORA; HUMANITIES; English language; Engelska språket;

    Sammanfattning : .... LÄS MER

  2. 2. Orphan Genes Bioinformatics : Identification and properties of de novo created genes

    Författare :Walter Basile; Arne Elofsson; Diethard Tautz; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; bioinformatics; de novo; orphans; evolutionary genetics; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Even today, many genes are without any known homolog. These "orphans" are found in all species, from Viruses to Prokaryotes and Eukaryotes. For a portion of these genes, we might simply not have enough data to find homologs yet. LÄS MER

  3. 3. Discovery of Novel Receptors for Lipid Mediators - a study leading to the identification of receptors involved in metabolism and the immune system

    Författare :Niclas Nilsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; Thiazolidinedione; SCFA; FFA; FFA2R; FFA1R; GPR43; GPR41; GPR40; BLT2; GPCR; Orphan; Receptor;

    Sammanfattning : Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. LÄS MER

  4. 4. G Protein-Coupled Receptors; Discovery of New Human Members and Analyses of the Entire Repertoires in Human, Mouse and Rat

    Författare :David E. Gloriam; Helgi Schiöth; Robert Fredriksson; Darren Flower; Uppsala universitet; []
    Nyckelord :Bioinformatics; G protein-coupled receptor; GPCR; Bioinformatics; Evolution; Orphan; Rhodopsin; Adhesion; Phylogeny; Bioinformatik;

    Sammanfattning : G protein-coupled receptors (GPCRs) are signal mediators that have a prominent role in the regulation of physiological processes and they make up the targets for 30-45% of all drugs. Papers I and II describe the discovery of new human GPCRs belonging to the Rhodopsin family, a family which contains many common drug targets. LÄS MER

  5. 5. Orphan source detection in mobile gamma-ray spectrometry - Improved techniques for background assessment

    Författare :Peder Kock; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gamma spectrometry; airborne; car-borne; radioactive; orphan sources; hypothesis testing; background radiation;

    Sammanfattning : Hazardous radioactive sources out of regulatory control are referred to as orphan sources. Focussing on gamma-emitting orphan sources, this thesis describes methods that can be used in mobile gamma-ray spectrometry to perform real-time discrimination between an actual source signal and the signal due to the natural radiation background. LÄS MER