Sökning: "Organs-on-chips"

Hittade 2 avhandlingar innehållade ordet Organs-on-chips.

1. 1. Organs-on-chips for the pharmaceutical development process : design perspectives and implementations

   Författare :Jonas Christoffersson; Carl-Fredrik Mandenius; Danny van Noort; Peter Sartipy; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Organs-on-chips; cell culture models; pharmaceutical development; microfluidics;

   Sammanfattning : Organs-on-chips are dynamic cell culture devices created with the intention to mimic organ function in vitro. Their purpose is to assess the toxicity and efficacy of drugs and, as early as possible in the pharmaceutical development process, predict the outcome of clinical trials. LÄS MER

3. 2. Development and Applications of Microfluidic Devices for Liver-on-a-Chip Studies

   Författare :Philip Dalsbecker; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Microfluidics; Microphysiological system; Liver-on-a-Chip; Organ-on-a-chip; Hepatocytes; Induced pluripotent stem cells; iPSC; HepG2; LX-2; on-chip differentiation; PDMS; Microfabrication; Shear stress;

   Sammanfattning : Modeling the human physiology in vitro is a challenging task, yet one of importance for the development of drugs and the study of diseases. To better address the complexities of human organs, microfluidic systems called organs-on-chips are being developed to emulate organ-specific environments for cell culture. LÄS MER