Sökning: "Oral glucose tolerance tests"

Visar resultat 6 - 10 av 19 avhandlingar innehållade orden Oral glucose tolerance tests.

  1. 6. Mechanism-Based Modeling of the Glucose-Insulin Regulation during Clinical Provocation Experiments

    Författare :Petra Jauslin-Stetina; Mats Karlsson; Nicolas Frey; Philippe Jacqmin; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Glucose homeostasis; Type 2 diabetes; IVGTT; OGTT; Meal test; Circadian variation; Mechanism-based; NONMEM; Farmakokinetik Farmakoterapi;

    Sammanfattning : Type 2 diabetes is a complex chronic metabolic disorder characterized by hyperglycemia associated with a relative deficiency of insulin secretion and a reduced response of target tissues to insulin. Considerable efforts have been put into the development of models describing the glucose-insulin system. LÄS MER

  3. 7. Glucose regulation and coronary artery disease : studies on prevalence, recognition and prognostic implications

    Författare :Malgorzata Zofia Bartnik; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Glucose metabolism; coronary artery disease; classification; prevalence; prognosis; risk oral glucose tolerance test; diabetes mellitus;

    Sammanfattning : Coronary artery disease and diabetes mellitus type 2 represent chronic diseases of substantial and growing prevalence. Their coincidence is common, markedly enhancing mortality and morbidity. The risk for cardiovascular disease increases along a spectrum of blood glucose concentrations from levels regarded as normal. LÄS MER

  4. 8. Peripheral polyneuropathy in type 2 diabetes mellitus and impaired glucose tolerance. Correlations between morphology, neurophysiology, and clinical findings

    Författare :Soley Thrainsdottir; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nerve conduction studies; skin biopsy; intraepidermal nerve fibers; Diabetic neuropathy; sural nerve pathology; body mass index; quantitative sensory testing; vibrotactile sense;

    Sammanfattning : Diabetic peripheral polyneuropathy (PN) is a common and serious complication of diabetes. The prevalence of PN is rising with the global burden of type 2 diabetes. The causal mechanisms of PN are not fully understood, but both vascular and metabolic factors play a role. LÄS MER

  5. 9. Diabetes mellitus, glucose abnormalities and acute coronary syndromes : studies on prevalence, risk and impact of treatment

    Författare :Anna Norhammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diabetes; glucose tolerance; hyperglycemia; prognosis; risk; mortality; prevalence; myocardial infarction;

    Sammanfattning : Background: Persons with diabetes mellitus and impaired glucose tolerance are at increased risk for cardiovascular disease.The prevalence of known diabetes among patients with acute myocardial infarction, about 20%, is expected to increase in the coming decades. LÄS MER

  7. 10. Dysglycaemia and cardiovascular disease. Aspects on screening, management, and prognosis

    Författare :Giulia Ferrannini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Dysglycaemia, in this thesis defined as impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), is a major risk factor for cardiovascular disease (CVD). International guidelines recommend screening for dysglycaemia and target-driven lifestyle and pharmacological management in people with high cardiovascular (CV) risk or established CVD for both men and women. LÄS MER