Sökning: "Oral glucose tolerance tests"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Oral glucose tolerance tests.

  1. 1. Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus

    Författare :Magnus Ekelund; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral glucose tolerance tests; Genetics; Autoimmunity; Insulin sensitivity; Gestational diabetes mellitus; Insulin secretion; HbA1c; Fasting glucose; FTO-gene; Postpartum diabetes;

    Sammanfattning : The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited through a regional screening programme in which oral glucose tolerance tests (OGTTs) are routinely offered to all pregnant women. LÄS MER

  2. 2. Oral glucose tolerance test as a prognostic tool in patients with Acute Coronary Syndrome

    Författare :Catarina Djupsjö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Background: Disturbances of glucose metabolism such as type 2 diabetes and impaired glucose tolerance are established risk factors for cardiovascular disease and mortality. The disturbances lead to hyperglycaemia and the most common methods to diagnose hyperglycaemia are HbA1c, oral glucose tolerance test (OGTT) and fasting plasma glucose (FPG). LÄS MER

  3. 3. Sampling from a suction induced mini-erosion in human skin. Methodological studies

    Författare :Christer Svedman; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular permeability; neurogenic inflammation; glucose; diabetes mellitus; interstitial fluid; transdermal; skin; sampling; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Dermal interstitial fluid (IF) was extracted serially and painlessly by brief suction for as long as 6 days. The erosion was otherwise kept occluded, Sample volumes exceded those required for measuring a wide range of biological substances. Epidermal regeneration was rapid. LÄS MER

  4. 4. Mechanism-Based Modelling of Clinical and Preclinical Studies of Glucose Homeostasis

    Författare :Oskar Alskär; Maria C Kjellsson; Mats O Karlsson; Jenny Y. Chien; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose homeostasis; pharmacometrics; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Sammanfattning : Glucose is an important nutrient and energy source in the body. However, too high concentration in the blood is harmful and may lead to several complications developing over time. It was estimated that 5 million people in the world died from complications related to diabetes during 2015. LÄS MER

  5. 5. Mechanism-Based Modeling of the Glucose-Insulin Regulation during Clinical Provocation Experiments

    Författare :Petra Jauslin-Stetina; Mats Karlsson; Nicolas Frey; Philippe Jacqmin; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Glucose homeostasis; Type 2 diabetes; IVGTT; OGTT; Meal test; Circadian variation; Mechanism-based; NONMEM; Farmakokinetik Farmakoterapi;

    Sammanfattning : Type 2 diabetes is a complex chronic metabolic disorder characterized by hyperglycemia associated with a relative deficiency of insulin secretion and a reduced response of target tissues to insulin. Considerable efforts have been put into the development of models describing the glucose-insulin system. LÄS MER