Sökning: "Optimality Criterion"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Optimality Criterion.

1. 1. Applied Adaptive Optimal Design and Novel Optimization Algorithms for Practical Use

   Författare :Eric Strömberg; Andrew Hooker; Mats Karlsson; Timothy Waterhouse; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nonlinear Mixed Effects Models; Pharmacometrics; Fisher Information Matrix; Approximation; Optimality Criterion; Parallelization; Model Based Adaptive Optimal Design; Pharmaceutical Science; Farmaceutisk vetenskap;

   Sammanfattning : The costs of developing new pharmaceuticals have increased dramatically during the past decades. Contributing to these increased expenses are the increasingly extensive and more complex clinical trials required to generate sufficient evidence regarding the safety and efficacy of the drugs. LÄS MER

3. 2. Multivariate Aspects of Phylogenetic Comparative Methods

   Författare :Krzysztof Bartoszek; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; General Linear Model; Ornstein-Uhlenbeck process; Multivariate phylogenetic comparative method; Evolutionary model; Adaptation; Optimality; Measurement error; Regression; Adaptation; Major-axis regression; Reduced major-axis regression; Structural equation; Allometry; Phylogenetic inertia; Allometry;

   Sammanfattning : his thesis concerns multivariate phylogenetic comparative methods. We investigate two aspects of them. The first is the bias caused by measurement error in regression studies of comparative data. We calculate the formula for the bias and show how to correct for it. LÄS MER

4. 3. Multicriteria optimization for managing tradeoffs in radiation therapy treatment planning

   Författare :Rasmus Bokrantz; Anders Forsgren; Karl-Heinz Küfer; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; multicriteria optimization; robust optimization; Pareto optimality; Pareto surface approximation; Pareto surface navigation; intensity-modulated radiation therapy; volumetric-modulated arc therapy; intensity-modulated proton therapy; Optimering; flermålsoptimering; robust optimering; Paretooptimalitet; Paretofrontsapproximation; Paretofrontsnavigering; intensitetsmodulerad strålterapi; rotationsterapi; intensitetsmodulerad protonterapi;

   Sammanfattning : Treatment planning for radiation therapy inherently involves tradeoffs, such as between tumor control and normal tissue sparing, between time-efficiency and dose quality, and between nominal plan quality and robustness. The purpose of this thesis is to develop methods that can facilitate decision making related to such tradeoffs. LÄS MER

5. 4. Optimization Algorithms for System Analysis and Identification

   Författare :Ragnar Wallin; Alf Isaksson; Anders Hansson; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : Optimization is a powerful and frequently used tool in many fields of research. In this thesis two relevant and important problems from robust control system analysis and system identification are solved using optimization algorithms. LÄS MER

7. 5. Optimal Control of Partial Differential Equations in Optimal Design

   Författare :Jesper Carlsson; Anders Szepessy; Peter Hansbo; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimal design; Numerical analysis; Numerisk analys;

   Sammanfattning : This thesis concerns the approximation of optimally controlled partial differential equations for inverse problems in optimal design. Important examples of such problems are optimal material design and parameter reconstruction. In optimal material design the goal is to construct a material that meets some optimality criterion, e.g. LÄS MER