Sökning: "Open lung approach"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Open lung approach.
1. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung
Sammanfattning : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. LÄS MER
2. Hemodynamic Effects of Lung Function Optimization in Experimental Acute Respiratory Distress Syndrome
Sammanfattning : Acute Respiratory Distress Syndrome (ARDS) is a severe pulmonary inflammation affecting thousands of patients every year in Sweden and has a mortality of 30-50%. Mechanical ventilation (MV) is usually necessary, but could per se augment the inflammation and contribute to mortality. LÄS MER
3. Airway pressure release ventilation : A systematic experimental approach
Sammanfattning : Airway pressure release ventilation (APRV) is a ventilatory mode which allows unrestrictedspontaneous breathing (SB) throughout the ventilatory cycle. If SB is insufficient, mechanicalventilatory support is achieved by brief periodic decreases of the airway pressure below the CPAPlevel. LÄS MER
4. Immunopeptidomics and autoantigens of interstitial lung diseases
Sammanfattning : We investigate Sarcoidosis and Idiopathic Pulmonary Fibrosis, IPF, to find markers for early fibrosis development. The aetiologies for both diseases are unknown and there is no specific treatment, moreover, there is a lack of diagnostic biomarkers for both diagnose and disease activity. LÄS MER
5. Regional Lung Kinetics of Ventilator-Induced Lung Injury and Protective-Ventilation Strategies Studied by Dynamic Positron Emission Tomography
Sammanfattning : Mechanical ventilation in itself can harm the lung and cause ventilator-induced lung injury (VILI), which can induce or aggravate acute respiratory distress syndrome (ARDS). Much debate remains over pivotal concepts regarding the pathophysiology of VILI, especially about the precise contribution, kinetics, and primary role of potential VILI mechanisms. LÄS MER