Sökning: "On angiogenesis modulation"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden On angiogenesis modulation.

  1. 1. On angiogenesis modulation

    Författare :Mattias Kalén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During evolution, the transition from unicellular to multicellular organisms required the origin of a transport system capable of interconnecting specialized cells throughout the body of the organism. In higher animals, this route of transportation is the cardiovascular system, which allows gas exchange, and transport of immune cells, hormones, macromolecules, nutrients and waste products. LÄS MER

  3. 2. Modulation of Angiogenesis by Laminins and Heparan Sulfate

    Författare :Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. LÄS MER

  4. 3. Modulation of angiogenesis in adult rat brain - effect of aging, stress, environmental enrichment and antidepressant treatment

    Författare :Joakim Ekstrand; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; corticosterone; enrichment; electroconvulsive seizures; Angiogenesis; neurogenesis;

    Sammanfattning : Neurogenesis and angiogenesis are stimulated by a number of antidepressant treatments, and cellular plasticity has emerged as a phenomenon with great relevance to the etiology and treatment of depression. In paper I we characterize how ECS-induced endothelial cell proliferation leads to vascularization of the adult rat hippocampus. LÄS MER

  5. 4. Therapeutic myocardial angiogenesis and its pharmacological modulation

    Författare :Anwar J Siddiqui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; arteriogenesis; ischemic heart; vascular endothelial growth factor; angiopoietin and receptor;

    Sammanfattning : Angiogenesis is the formation of new blood vessels induced by the proliferation and migration of endothelial cells. Because angiogenesis is a complex process, therapeutic efficacy may be improved by overexpression of combined angiogenic factors. LÄS MER

  7. 5. Regulation of the vascular smooth muscle cell phenotype

    Författare :Henrik Lindskog; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryonic stem cells; vascular smooth muscle cell; smooth muscle cell; pericyte; phenotypic modulation; lipoma preferred partner; ectra-cellular matrix; zinc finger protein 148;

    Sammanfattning : Smooth muscle cells (SMC) are present in many internal organs such as the blood vessels and the gastrointestinal channel. Their main functions are to provide stability to the tissue and to provide contractile capability. SMC are not terminally differentiated but can switch between several phenotypes, which is also known as phenotypic modulation. LÄS MER