Sökning: "Omeprazole"

Visar resultat 16 - 20 av 37 avhandlingar innehållade ordet Omeprazole.

  1. 16. Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection

    Författare :Speranta Banesaru; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental niches and hosts, including humans. The illnesses caused by various serovars in humans range from mild gastroenteritis to severe systemic disease such as typhoid fever that still cause an important number of casualties especially in developing countries. LÄS MER

  3. 17. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors

    Författare :Angela Äbelö; Mats Karlsson; Michael Looby; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

    Sammanfattning : Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing gastric acidity. Irreversible proton pump inhibitors (PPIs) inhibit gastric acid secretion effectively throughout the day by irreversibly inhibiting the gastric proton pump, H+, K+-ATPase, in the parietal cells. LÄS MER

  4. 18. Ecological disturbances and emergence of resistance in the oral and gastrointestinal microflora after drug exposure

    Författare :Christina Stark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ecology antimicrobial resistance oral gastrointestinal microflora B-lactamase enzyme induction.;

    Sammanfattning : The exposure of antimicrobial agents and antacids may disturb the ecological balance of the normal microflora. This influence often leads to decreased colonization resistance due to repression of sensitive bacteria and selection of resistant bacteria which have acquired resistance during therapy. LÄS MER

  5. 19. Treatment of helicobacter pylori infection : experimental and clinical studies

    Författare :Mikael Sörberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Helicobacter pylori; coccoid form; treatment; pharmacodynamics; resistance; serology Stockholm 1997;

    Sammanfattning : The general aims of the present study were to investigate the reason for failed H. pylori eradication, and to improve the recommendations for treating H. pylori infection. Our in vitro studies are based on microscopy, viable count and bioluminescence assay of bacterial adenosine triphosphate (ATP). LÄS MER

  7. 20. CYP2C19 and CYP2C9 : new aspects of pharmacogenetics and transcriptional regulation

    Författare :Jessica Mwinyi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytochrome P450s (CYPs) are responsible for approximately 75% of the phase I-dependent drug metabolism. Several important polymorphisms in these enzymes are known to significantly affect the individual drug response. LÄS MER