Sökning: "Oligonucleotide-peptide conjugates"

Hittade 1 avhandling innehållade orden Oligonucleotide-peptide conjugates.

  1. 1. Development of a novel methodology for the synthesis of oligonucleo-peptide conjugates

    Författare :Simone Zaramella; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antisense; Oligonucleotide-peptide conjugates; Solid-phase synthesis; Histidine; Protecting groups.;

    Sammanfattning : Peptide-oligonucleotide conjugates constitute a new class of antisense molecules that exhibit improved biological activity over standard oligonucleotide analogues. Currently, these oligomeric bioconjugates are prepared by either solution- or solid-phase techniques. LÄS MER