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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Atrial fibrillation and cause of death, sex differences in mortality, and anticoagulation treatment in low-risk patients

   Författare :Tommy Andersson; Ole Frøbert; Dritan Poçi; Egon Toft; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; Cerebral infarction; Anticoagulation; Cause of death; Mortality risk; Sex differences; CHA2DS2-VASc score;

   Sammanfattning : Background: Atrial fibrillation (AF) is the most common arrhythmia but information on cause of death in patients with AF is sparse, and whether individuals at low risk of cerebral infarction (CVL) should receive antico-agulant medication is controversial. Studies of sex differences with respect to mortality risk have shown conflicting results. LÄS MER

3. 2. Immobilization as a risk factor for arterial and venous thrombosis

   Författare :Karin Arinell; Ole Frøbert; Kjeld Christensen; Tal Hörer; Joakim Alfredsson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; arterial thrombosis; atherosclerosis; cystatin C; cholesterol; platelet activation; platelet aggregation; immobilization;

   Sammanfattning : Aim: Immobilization and a sedentary lifestyle are correlated with an elevated risk of both arterial and venous thrombosis. The goal of this research was to investigate whether markers associated with cardiovascular disease risk are altered during long term immobilization in a human model and in the brown bear, which survives annual cycles of long-term immobilization. LÄS MER

4. 3. Coronary artery disease and prognosis in relation to cardiovascular risk factors, interventional techniques and systemic atherosclerosis

   Författare :Fredrik Calais; Ole Fröbert; Jerzy Leppert; Bo Lagerqvist; Stefan K James; Douwe E. Atsma; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Myocardial infarction; Coronary artery disease; Extra-cardiac artery disease; Coronary stent; Thrombus aspiration; physical inactivity; Prognosis;

   Sammanfattning : Aim: To evaluate the prognosis associated with location and severity of coronary and systemic atherosclerosis in patients with coronary artery disease (CAD) in relation to risk factors and interventional techniques.Methods: The thesis comprised six longitudinal studies based on three patient cohorts: The Swedish Coronary Angiography and Angioplasty Registry, the Västmanland Myocardial Infarction Survey, and the Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia study, to evaluate clinical outcome relative to coronary lesion location and severity, extracoronary artery disease (ECAD), intervention techniques, and leisuretime physical inactivity (LTPI). LÄS MER

5. 4. Novel and Traditional Risk Factors for Coronary Artery Disease : Role of Coronary Artery Calcium, Lipidomics, Psychosocial Factors and Diet

   Författare :Demir Djekic; Ole Fröbert; Annika Rosengren; Tuulia Hyötyläinen; Anna M. Nordenskjöld; Magnus Bäck; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Novel risk factors; coronary artery calcium; lipidomics; lipidome; psychosocial factors; vegetarian diet; gut microbiota; metabolome;

   Sammanfattning : Background: The aim of the research reported in this thesis was to determine the association of novel and traditional risk factors with coronary artery calcium (CAC), a marker of subclinical coronary artery disease (CAD) in healthy individuals. In addition, we investigated the effects of a vegetarian, compared to a meat diet, on novel and traditional risk factors in patients with diagnosed CAD. LÄS MER

7. 5. Unrecognized myocardial infarction and cardiac biochemical markers in patients with stable coronary artery disease

   Författare :Anna Nordenskjöld; Bertil Lindahl; Ole Fröbert; Kai Eggers; Torbjørn Omland; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Unrecognized myocardial infarction; Coronary artery disease; Prevalence; Prognosis; Troponin; NT-proBNP; Galectin-3; Medicin; Medicine;

   Sammanfattning : Aim: The overarching aim of the thesis was to explore the occurrence and clinical importance of two manifestations of myocardial injury; unrecognized myocardial injury (UMI) and altered levels of cardiac biochemical markers in patients with stable coronary artery disease (CAD).Methods: A prospective multicenter cohort study investigated the prevalence, localization, size, and prognostic implication of UMI in 235 patients with stable CAD. LÄS MER