Sökning: "Octreotide"

Visar resultat 6 - 10 av 23 avhandlingar innehållade ordet Octreotide.

  1. 6. Growth Hormone and Gender. Studies in Healthy Adults and in Patients with Growth Hormone Disorders

    Författare :Britt Edén Engström; Uppsala universitet; []
    Nyckelord :Medical sciences; Growth hormone; gender; ambulation; oral contraceptives; epinephrine; GH treatment; age; E2-implant; IGF-I; octreotide; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The use of a new, more sensitive immunoassay for growth hormone (GH) revealed that the serum levels in men were lower than expected in sera drawn ambulatory in the morning after an overnight fast and that the gender difference was more than 10 times greater than reported. These observations led to a more thorough study on the impact of gender and sex steroids on the levels of GH and other hormones in ambulatory morning samples and over a 24-hour period. LÄS MER

  3. 7. The Regulation of Growth and Survival in Human Multiple Myeloma Cells by IGF-I Receptor Signaling

    Författare :Thomas Strömberg; Helena Jernberg Wiklund; Kenneth Nilsson; Anders Waage; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Multiple myeloma; IGF-IR; apoptosis; somatostatin; octreotide; dexamethasone; GSK-3; mTOR; rapamycin; RTK inhibitor; Patologi; Pathology; Patologi;

    Sammanfattning : Multiple myeloma (MM) is an incurable B-cell malignancy mainly localized to the bone marrow. Our aim was to examine the growth- and survival-promoting role of the IGF-IR and its downstream signaling components in MM cells to identify potential targets for therapy. LÄS MER

  4. 8. Förbättrad radionuklidterapi av neuroblastom

    Författare :Arman Romiani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radionuclide therapy; Neuroblastoma; Somatostatin analog; 177Lu-octreotate; 177Lu-octreotide; Lorlatinib; Combination therapy; Radiosensitizer;

    Sammanfattning : Today, about half of the children diagnosed with high-risk neuroblastoma (HR-NB) survive due to considerable treatment improvements during the last decades. However, there is still much to be done for the other half who are not cured with current treatments. LÄS MER

  5. 9. Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity

    Författare :Maria Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRRT; 177Lu-octreotate; 111In-octreotide; dosimetry; biokinetics; scintigraphy; conjugate view method; renal function; renal toxicity; lysine; DMSA; 99mTc-DTPA; 99mTc-DMSA;

    Sammanfattning : 177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. LÄS MER

  7. 10. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

    Författare :Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
    Nyckelord :Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

    Sammanfattning : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. LÄS MER