Sökning: "Oct-1"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Oct-1.

  1. 1. Epstein-Barr virus nuclear antigen 1, Oct and Groucho/TLE in control of promoter regulation

    Författare :Jenny Almqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EBV; Oct-1; Oct-2; Groucho; TLE; transcription; repression; latency;

    Sammanfattning : The human herpes virus Epstein-Barr virus (EBV) is carried by approximately 95% of the adult population. It can form a lifelong latent infection in the B-cells by avoiding our immune system. A latent EBV infection is usually asymptomatic but a few EBV associated cancer forms has been described (e.g. LÄS MER

  3. 2. Tripeptidyl-Peptidase II : Structure, Function and Gene Regulation

    Författare :Ann-Christin Lindås; Birgitta Tomkinson; Mikael Widersten; Ralf Morgenstern; Uppsala universitet; []
    Nyckelord :Biochemistry; gene regulation; protein expression; enzyme kinetics; tripeptidyl-peptidase II; proteasome; intracellular protein degradation; exopeptidase; Biokemi;

    Sammanfattning : The protein degradation process is of vital importance for the cell to maintain cellular functions. An important enzyme in this process is the multimeric tripeptidyl-peptidase II (TPP II). It removes tripeptides from a free N-terminus of the substrates. LÄS MER

  4. 3. Early stress, cortisol in hair and health among children in different psychosocial environments

    Författare :Jerker Karlén; Tomas Faresjö; Johnny Ludvigsson; Töres Theorell; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Psychosocial circumstances during early life are increasingly recognized as crucial, not only for the growing individual but also for health throughout life. A possible mechanism could be physiologic dysregulation due to stress. LÄS MER

  5. 4. Transcription factors involved in negative and positive gene regulation by glucocorticoids

    Författare :Nanthakumar Subramaniam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Steroid hormones, including glucocorticoids (GCs), control a wide variety of developmental and physiological responses in higher eukaryotic organisms. They pass through the plasma membrane and bind to specific receptor proteins inside the cell. LÄS MER

  7. 5. Transcriptional activation by Sp1 and the adenovirus E1A transactivator protein

    Författare :Anne-Christine Ström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Transcription is a key step in the regulation of gene expression. Activation of transcriptionrequires that the RNA polymerase receive both, regulatory signals from transcription factors,and initiate transcription at the correct location in the genome, at the promoter. LÄS MER