Avancerad sökning

Visar resultat 1 - 5 av 981 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Obesity Genetics : Functional Aspects of Four Genetic Loci Associated with Obesity and Body Mass

    Författare :Mathias Rask-Andersen; Helgi Schiöth; Ingrid Dahlman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Obesity is a complex disorder which has reached epidemic proportions in many parts of the world. Twin studies have demonstrated a high heritability for obesity. The subsequent appli-cation of genome wide association studies (GWAS) in the last decade have identified at least 32 genetic loci associated with body mass and obesity. LÄS MER

  3. 2. Insights on weight maintenance and impacts of obesity for two rural populations in the United States and Sweden

    Författare :Melissa Brower Scribani; Margareta Norberg; Lars Weinehall; Paul Jenkins; Julie Sorensen; Kirsten Mehlig; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Obesity trends; Premature mortality; Obesity prevention; Weight maintenance; Primary weight maintenance; Rural; United States; Sweden; Public health; Public health; folkhälsa;

    Sammanfattning : Background: Obesity is a serious public health concern worldwide, and nearly 40% of all adults in the United States and 21% in Sweden are now living with obesity. Efforts focusing mainly on weight loss have fallen short in reducing obesity prevalence. LÄS MER

  4. 3. Obesity and Increased Susceptibility : Role of FTO and MGAT1 Genetic Variants

    Författare :Josefin A Jacobsson; Robert Fredriksson; Helgi B Schiöth; Sadaf Farooqi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; BMI; SNP; haplotype; association study; FTO; MGAT1; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Sammanfattning : Obesity is a complex and a highly individualized disease and the molecular mechanisms behind this disorder need to be better elucidated. Identification of genes and genetic variants that are involved provide opportunities to establish a genetic understanding of the disease. LÄS MER

  5. 4. Pathogenesis of Obesity and Effects of Treatment. Clinical and Molecular Studies on Body Fat, Energy Balance, and Weight Loss

    Författare :Anders Gummesson; Göteborgs universitet; []
    Nyckelord :Obesity; Adipose tissue; Obesity treatment; Energy balance; Visceral obesity; Weight loss; Cancer; Human studies;

    Sammanfattning : Obesity is common and related to many health problems including various forms of cancer. The condition arises from the imbalance between food intake and energy expenditure, and is strongly influenced by genetic factors. LÄS MER

  7. 5. Environmental Contaminants and Obesity

    Författare :Monika Rönn; P. Monica Lind; Lars Lind; Jan Örberg; Merete Eggesbø; Uppsala universitet; []
    Nyckelord :Fischer 344; rat; obesity; adipose tissue; persistent organic pollutants; POPs; bisphenol A; BPA; pesticides; dioxin; PCB; DDT; apo A-I; adiponectin; leptin; ghrelin;

    Sammanfattning : Obesity is a worldwide problem affecting both children and adults. Genetic, physiological, environmental, psychological, social and economic factors interact in varying degrees, influencing body weight and fat distribution and the progress of obesity. LÄS MER