Sökning: "OVA"

Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet OVA.

1. 1. Remodeling of the pulmonary circulation - a novel response to allergic airway inflammation

   Författare :Kristina Rydell-Törmänen; Luftvägsinflammation; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular remodeling; OVA; HDM; asthma;

   Sammanfattning : Asthma is characterized, not only by inflammation but also by airway and vascular remodeling. Airway remodeling is established early in disease, structural alterations have been found in children, and is thought to contribute to asthma symptoms. Unfortunately, airway remodeling is considered difficult to reverse and it seldom resolves completely. LÄS MER

3. 2. Immunological tolerance to antigens in the intestine

   Författare :Malin Karlsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rat; oral tolerance; serum factor; normal gut flora; exosomes;

   Sammanfattning : The major part of the immune system is found in the epithelium and lamina propria of the gut. The distribution of the leukocytes is structured probably because the immune system has to distinguish between harmful microorganisms, food antigens and the normal gut flora. LÄS MER

4. 3. Regulation of innate and adaptive immune responses by Gram-positive and Gram-negative bacteria

   Författare :Anna Martner; Göteborgs universitet; []
   Nyckelord :Gram-positive; Gram-negative bacteria; Streptococcus pneumoniae; IL-12; autolysin; pneumolysin; CD4 T cells; monocytes macrophages; dendritic cells;

   Sammanfattning : Bacteria are classified as Gram-positive or Gram-negative, depending on their cell wall structure. The role of the bacterial cell wall in immune regulation is the focus of the current work. Most Gram-positive bacteria stimulate monocytes to produce large amounts of IL-12. LÄS MER

5. 4. Exosomes : immunomodulators in cancer and therapy

   Författare :Stefanie Hiltbrunner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Exosomes are nano-sized membrane vesicles derived from the late endosomal compartment. They are capable of transferring proteins, lipids and RNA between cells. B cell and dendritic cell (DC)-derived exosomes express major histocompatibility complex (MHC) class I and II, as well as costimulatory molecules (CD80/86) and can initiate T cell responses. LÄS MER

7. 5. Antibody Feedback Regulation : From Epitope Masking to T Helper Cell Activation

   Författare :Andrew Getahun; Birgitta Heyman; Hans-Gustaf Ljunggren; Daniel Conrad; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immune regulation; B cells; T cells; Antibodies; Fc Receptors; Antigen presentation; Transgenic Knockout Mice; Immunologi; Immunology; Immunologi;

   Sammanfattning : Antibodies have the ability to influence the antibody response against the very antigen they are specific for, in a process called antibody feedback regulation. Depending on the nature of the antigen, the antibody response can be either enhanced or almost completely inhibited. LÄS MER