Sökning: "OSS development"

Visar resultat 16 - 20 av 264 avhandlingar innehållade orden OSS development.

  1. 16. Aspects of T cell development contributing to autoimmunity

    Författare :Maria Carlsén; Diabetes - immunovirologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FTOC; T cell development; Type 1 diabetes; p53; Insulin; NOD; Negative selection; TGF-β; Tolerance; Thymus; Conditional cre lox knock out; Autoimmunity;

    Sammanfattning : Autoimmunity, such as type 1 diabetes (T1D), arises as a result of tolerance breakdown against host tissues, i.e. the β-cells. Central tolerance is established during thymic T cell development and defects in key events during this process could contribute to the pathogenesis of autoimmune diseases. LÄS MER

  3. 17. Development and applications of NMR relaxation methods to study protein and ligand dynamics

    Författare :Sven Wernersson; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear magnetic resonance; NMR; NMR relaxation; Method development; Protein dynamics; BRD4; Galectin 3; Kärnmagnetisk resonansspektroskopi; proteindynamik; Metodutveckling; NMR; BRD4; Galektin 3;

    Sammanfattning : This thesis involves the study of proteins. These molecules exist in many variants, and perform most of our bodily functions. This includes signaling (for example the presence of capsaicin, which makes food spicy), molecular transport (including oxygen), catalysis (including food digestion) and part of our body structure (such as muscles). LÄS MER

  4. 18. Functional collaboration between HLH transcription factors in B cell development

    Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

  5. 19. The Multilingual Forest : Investigating High-quality Parallel Corpus Development

    Författare :Yvonne Adesam; Martin Volk; Joakim Nivre; Koenraad de Smedt; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; treebank; syntax; alignment; corpus; annotation projection; multilingual; tagging; parsing; datorlingvistik; Computational Linguistics;

    Sammanfattning : This thesis explores the development of parallel treebanks, collections of language data consisting of texts and their translations, with syntactic annotation and alignment, linking words, phrases, and sentences to show translation equivalence. We describe the semi-manual annotation of the SMULTRON parallel treebank, consisting of 1,000 sentences in English, German and Swedish. LÄS MER

  7. 20. I oss är en mångfald levande : Karin Boye som kritiker och prosamodernist

    Författare :Gunilla Domellöf; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Karin Boye; Sweden in the 1930 s; literary criticism; modernism; feminism;

    Sammanfattning : The aim of this dissertation is to describe Karin Boye as a critic and a modernist novel writer. The material consists of Karin Boye's works, articles from newspapers and periodicals and secondary sources. The method applied is a critical investigation of basic hermeneutic principles with special reference to sexual/textual politics. LÄS MER