Sökning: "Nuclear Proteins"

Visar resultat 11 - 15 av 548 avhandlingar innehållade orden Nuclear Proteins.

  1. 11. Macrophage Activation and AP-1 in Atherosclerosis

    Författare :Maria Stollenwerk; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Proteins; enzymology; Proteiner; enzymologi; Cardiovascular system; carotid plaque; interleukin-1b; caspase-1.; very low-density lipoprotein; fatty acids; activator protein-1; inflammation; Atherosclerosis; nuclear factor-kB; macrophages; tumor necrosis factor;

    Sammanfattning : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. LÄS MER

  3. 12. Isolation and functional characterization of Hrp65-binding proteins in Chironomus tentans

    Författare :Eva Kiesler; Neus Visa; Benjamin Blencowe; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene expression; RNA-binding proteins; mRNA biogenesis; nuclear structure; Molecular biology; Molekylärbiologi;

    Sammanfattning : It is well-established that the organization of nuclear components influences gene expression processes, yet little is known about the mechanisms that contribute to the spatial co-ordination of nuclear activities. The salivary gland cells of Chironomus tentans provide a suitable model system for studying gene expression in situ, as they allow for direct visualization of the synthesis, processing and export of a specific protein-coding transcript, the Balbiani ring (BR) pre-mRNA, in a nuclear environment in which chromatin and non-chromatin structures can easily be distinguished. LÄS MER

  4. 13. Protein Quality Control at the Inner Nuclear Membrane – The Asi complex in Saccharomyces cerevisiae

    Författare :Marina Pantazopoulou; Per Ljungdahl; Jaspersen Sue; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nuclear envelope; nuclear quality control NQC ; ubiquitin; proteasome; inner nuclear membrane-associated degradation INMAD ; Cell Biology; cellbiologi;

    Sammanfattning : The nuclear envelope is a barrier comprised of outer and inner membranes that separate the cytoplasm from the nucleoplasm. The outer (ONM) and inner (INM) membranes have different physical characteristics and protein compositions. LÄS MER

  5. 14. Modulation of nuclear receptor function by interacting proteins

    Författare :Waffa Osman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nuclear receptors are a family of transcription factors involved in many biological processes. They represent key potentials as therapeutic targets for several clinical conditions such as diabetes, obesity, cardiovascular disease and cancer, because their activity is modulated by small molecules. LÄS MER

  7. 15. Identification and characterization of protein-protein interactions in the nuclear envelope

    Författare :Balaje Vijayaraghavan; Einar Hallberg; Katherine Wilson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope; Samp1; Emerin; Ran and transmembrane proteins; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nuclear envelope forms the interface between the nucleus and the cytoplasm. The nuclear envelope consists of the two concentric lipid membranes, the nuclear pores and the nuclear lamina. The inner nuclear membrane contains hundreds of unique transmembrane proteins showing high tissue diversity. LÄS MER