Sökning: "Non-small cell lung cancer"

Visar resultat 1 - 5 av 74 avhandlingar innehållade orden Non-small cell lung cancer.

  1. 1. Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling

    Författare :Christina Karlsson; Karin Piehl-Aulin; Ulf Tidefelt; Gisela Helenius; Leif Johansson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-small cell lung carcinoma; estrogen receptor; epidermal growth factor receptor; HER-4; tissue microarray; immunohistochemistry; smoking habits; in situ hybridisation; Onkologi; Oncology;

    Sammanfattning : Non-small cell lung carcinoma is a leading cause of cancer mortality worldwide. There are gender and smoking associated differences both in tumour types and clinical outcome. Squamous cell carcinomas (SCC) are more frequent among smoking men while females develop adenocarcinomas (ADCA). LÄS MER

  2. 2. Genomic characterization of non-small cell lung cancer - clinical and molecular implications

    Författare :Anna F Karlsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung cancer; histology; non-small cell lung cancer; gene expression; gene fusion; Methylation;

    Sammanfattning : Lung cancer accounts for 1.6 million cancers annually and 1.3 million deaths per year make the disease the deadliest type of cancer. Smoking is the most prominent cause. LÄS MER

  3. 3. Biomarkers in mesothelioma and non-small cell lung cancer - Investigation of cytological specimens with correlation to histology

    Författare :Mohammed S. I. Mansour; LUCC: Lunds universitets cancercentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarker; Cytology; Cytology-histology correlation CHC ; Cytopathology; Effusion cytology; Genetic alteration; Histology; Histopathology; Immunohistochemistry; Immunotherapy; Lung cancer; Lung cytology; Mesothelioma; Molecular analysis; Non-small cell lung cancer; Oncologic pathology; Therapeutic pathology;

    Sammanfattning : .... LÄS MER

  4. 4. The Molecular Epidemiology of Non-Small Cell Lung Cancer

    Författare :Johan Isaksson; Johan Botling; Eva Brandén; Hirsh Koyi; Aija Knuuttila; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NSCLC; Lung Cancer; Epidemiology; Genetics; KRAS; Pathology; Biomarkers; Oncology; Onkologi;

    Sammanfattning : The aim of this thesis was to explore the role of a spectrum of biomarkers, for disease classification or predictors of treatment outcomes in non-small cell lung cancer (NSCLC).Paper I examined the impact of systemic inflammation on the clinical outcome of NSCLC patients. LÄS MER

  5. 5. Angiogenesis Related Markers In Non-Small Cell Lung Cancer

    Författare :Daniel Brattström; Ola Brodin; Gunnar Wagenius; Torgny Rasmusen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; NSCLC; Therapy; Angiogenesis; VEGF; bFGF; Microvessel density; Survival; Onkologi; Oncology; Onkologi;

    Sammanfattning : This thesis investigated the predictive and the prognostic powers of angiogenesis related markers in both operable and inoperable non-small cell lung cancer (NSCLC) patients.In the first and second study, we investigated the serological fractions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in 2 cohorts of patients with either operable or inoperable NSCLC. LÄS MER