Sökning: "Non-Insulin-Dependent: blood"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Non-Insulin-Dependent: blood.

  1. 1. Pharmacokinetics - Effect Relations of Glibenclamide and its Metabolites in Humans

    Författare :Tony S Rydberg; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal insufficiency.; insulin; glucose; non-insulin dependent; diabetes mellitus; pharmacodynamic modelling; pharmacodynamics; pharmaco-kinetics; HPLC method; Glibenclamide; sulphonylurea; metabolites; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Glibenclamide (Gb) is the most commonly employed sulphonylurea worldwide for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). There has been uncertainty concerning its pharmacokinetics (PK) and pharmacodynamics (PD). LÄS MER

  3. 2. Hyperglycaemia and diabetic eye complications - a clinical and epidemiological study

    Författare :Marianne Henricsson; Oftalmologi (Malmö); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mortality; blindness; cataract surgery; oral antihyperglycaemic agents; hyperglycaemia; insulin treatment; non-insulin dependent diabetes mellitus; diabetic retinopathy; insulin-dependent diabetes mellitus; Ophtalmology; Oftalmologi;

    Sammanfattning : Aim: To study the relationship between hyperglycaemia and the onset/progression of retinopathy, blindness/moderate visual impairment or death, as well as the impact of improved glycaemic control on retinopathy in patients with non-insulin-dependent diabetes mellitus (NIDDM). Methods: Between January 1990 and October 1995 a total of 3,220 diabetic patients were enrolled in a programme for control and screening for retinopathy. LÄS MER

  4. 3. The regulation of muscle interstitial insulin, nutrients and blood flow in insulin resistant models. An investigation using the euglycemic insulin clamp and microdialysis techniques

    Författare :Maria Niklasson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; skeletal muscle; glucose uptake; transcapillary transport; interstitial fluid; euglycemic insulinclamp; microdialysis; blood flow; vasodilation;

    Sammanfattning : Insulin resistance, mainly located to the skeletal muscle tissue, is one prominent feature in thedevelopment of non insulin-dependent diabetes mellitus (NIDDM) and further, associated withcardiovascular diseases. In this context the importance of blood flow for insulin sensitivity has beensuggested by regulating the delivery of insulin and nutrients to the target cells. LÄS MER

  5. 4. Physical exercise and electrical stimulation in the management of metabolic, cardiovascular and skeletal-muscle alterations in people with tetraplegia

    Författare :Nils Hjeltnes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Spinal cord injury; glucose metabolism; electrical stimulation; exercise; skeletal muscle; body composition; catecholamines; blood pressure.;

    Sammanfattning : Interruption of the spinal cord at the cervical level leads to permanent extensive motor paralysis, serious autonomic regulation deficits and profound short term and long term metabolic disorders. The defects play a decisive role for the tetraplegic individuals future function and health. LÄS MER

  7. 5. Primary Care as an Arena For Primary, Secondary, and Tertiary Vardiovascular Disease Prevention

    Författare :Ingvar Ovhed; Allmänmedicin och samhällsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; samhällsmedicin; Socialmedicin; Social medicine; primary health care; Opportunistic screening; consultation; primary prevention; secondary prevention; tertiary prevention; hypercholesterolaemia; hypertension; smoking; coronary disease; NIDDM; smoking cessation; awareness; general pract; self-monitoring; Kardiovaskulära systemet;

    Sammanfattning : Cardiovascular disease prevention has been a challenge for research for decades. The studies of this thesis were designed to investigate the role of health professionals in everyday clinical work based upon the concept of comprehensive primary care consultation. LÄS MER