Sökning: "Non insulin dependent diabetes"

Visar resultat 16 - 20 av 77 avhandlingar innehållade orden Non insulin dependent diabetes.

1. 16. Why do children get diabetes? : A study on some genetical, immunological and environmental factors

   Författare :Ulf Samuelsson; Hans Åkerblom; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Insulin dependent diabetes mellitus (IDDM) is one of the most common and serious chronic disorders of childhood. Despite advances in the knowledge about the cause of IDDM during the last decades the etiology still remains incompletely understood but is probably due to a complex network of genetic, immunological and environmental factors. LÄS MER

3. 17. Post-transplantation Hypercholesterolaemia

   Författare :Osama Al Rayyes; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thiazolidinediones; transplantation; low density lipoprotein; insulin; indomethacin; hydrocortisone; fluvastatin; flufenamic acid; Cholesterol; cyclosporine; troglitazone.; Immunology; serology; Immunologi; serologi;

   Sammanfattning : The multidrug regimen, cyclosporine, corticosteroids, and azathioprine, is used in transplantation centres to prevent organ rejection. Several clinical studies have shown that cyclosporine and corticosteroids to cause increases in low density lipoprotein (LDL)-cholesterol, with subsequent development of atherosclerosis. LÄS MER

4. 18. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

   Författare :Malou Friederich Persson; Fredrik Palm; Richard K. Porter; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. LÄS MER

5. 19. Metab-Immune analysis of the non-obese diabetic mouse

   Författare :Viqar Banday; Kristina Lejon; Åsa Andersson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NOD mouse; Type 1 diabetes; B cells; glutamic acid; metabolomics; immunologi; Immunology;

   Sammanfattning : Type 1A diabetes mellitus or T1D is a chronic disease characterized by T cell mediated destruction of the insulin producing β cells in the islets of Langerhans. The classical symptoms include high glucose levels in urine and blood, polyuria, and polydipsia. LÄS MER

7. 20. Selective insulin signaling in the pancreatic beta-cell via the two insulin receptor isoforms

   Författare :Sabine Uhles; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Insulin receptor; signal transduction; gene expression regulation; insulin; glucokinase; cfos; pancreatic beta cell; membrane microdomains; green fluorescent protein.;

   Sammanfattning : Insulin exhibits pleiotropic effects that are tissue- as well as development-dependent. However, the mechanisms by which insulin gains selective effects are poorly understood. Selectivity in insulin signaling is currently discussed as the result of the activation of specific signal transduction pathways. LÄS MER